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Michael A Kalwat
Michael A Kalwat
Assistant Investigator, Indiana Biosciences Research Institute & Adjunct Faculty, IUSM
Verified email at indianabiosciences.org - Homepage
Title
Cited by
Cited by
Year
Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells
MA Kalwat, DC Thurmond
Experimental & molecular medicine 45 (8), e37-e37, 2013
1632013
Mechanisms of the amplifying pathway of insulin secretion in the β cell
MA Kalwat, MH Cobb
Pharmacology & therapeutics 179, 17-30, 2017
1492017
Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis
JL Jewell, E Oh, L Ramalingam, MA Kalwat, VS Tagliabracci, L Tackett, ...
Journal of Cell Biology 193 (1), 185-199, 2011
952011
Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms
E Oh, MA Kalwat, MJ Kim, M Verhage, DC Thurmond
Journal of Biological Chemistry 287 (31), 25821-25833, 2012
912012
A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells
MA Kalwat, SM Yoder, Z Wang, DC Thurmond
Biochemical pharmacology 85 (6), 808-816, 2013
792013
Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosis
DA Wiseman, MA Kalwat, DC Thurmond
Journal of Biological Chemistry 286 (18), 16344-16354, 2011
592011
Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis
MA Kalwat, DA Wiseman, W Luo, Z Wang, DC Thurmond
Molecular endocrinology 26 (1), 128-141, 2012
552012
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion
EM Kepner, SM Yoder, E Oh, MA Kalwat, Z Wang, LA Quilliam, ...
American Journal of Physiology-Endocrinology and Metabolism 301 (6), E1072-E1080, 2011
522011
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity
L Ramalingam, E Oh, SM Yoder, JT Brozinick, MA Kalwat, AJ Groffen, ...
Diabetes 61 (10), 2424-2432, 2012
512012
Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
G Hernandez, T Luo, TA Javed, L Wen, MA Kalwat, K Vale, F Ammouri, ...
Science translational medicine 12 (525), eaay5186, 2020
472020
Insulin Promoter-Driven Gaussia Luciferase-Based Insulin Secretion Biosensor Assay for Discovery of β-Cell Glucose-Sensing Pathways
MA Kalwat, C Wichaidit, AY Nava Garcia, MK McCoy, K McGlynn, ...
ACS sensors 1 (10), 1208-1212, 2016
422016
Isoxazole alters metabolites and gene expression, decreasing proliferation and promoting a neuroendocrine phenotype in β-cells
MA Kalwat, Z Huang, C Wichaidit, K McGlynn, S Earnest, C Savoia, ...
ACS chemical biology 11 (4), 1128-1136, 2016
362016
The pancreatic ß-cell response to secretory demands and adaption to stress
MA Kalwat, D Scheuner, K Rodrigues-dos-Santos, DL Eizirik, MH Cobb
Endocrinology 162 (11), bqab173, 2021
172021
Sucralose activates an ERK1/2–ribosomal protein S6 signaling axis
ML Guerra, MA Kalwat, K McGlynn, MH Cobb
FEBS Open Bio 7 (2), 174-186, 2017
122017
High-throughput screening for insulin secretion modulators
MA Kalwat
Exocytosis and endocytosis: methods and protocols, 131-138, 2021
82021
Chromomycin A2 potently inhibits glucose-stimulated insulin secretion from pancreatic β cells
MA Kalwat, IH Hwang, J Macho, MG Grzemska, JZ Yang, K McGlynn, ...
Journal of General Physiology 150 (12), 1747-1757, 2018
82018
α2-Adrenergic Disruption of β Cell BDNF-TrkB Receptor Tyrosine Kinase Signaling
MA Kalwat, Z Huang, DD Binns, K McGlynn, MH Cobb
Frontiers in Cell and Developmental Biology 8, 576396, 2020
42020
Measuring relative insulin secretion using a co-secreted luciferase surrogate
M Kalwat, MH Cobb
JoVE (Journal of Visualized Experiments), e59926, 2019
42019
BDNF/TrkB signaling in pancreatic islet beta cells
M Kalwat, Z Huang, K McGlynn, MH Cobb
Seminars in fetal & neonatal medicine, 2018
32018
Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function
K Rodrigues-dos-Santos, G Roy, DD Binns, MG Grzemska, LF Barella, ...
Endocrinology 163 (7), bqac081, 2022
22022
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