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Alexander P Bye
Alexander P Bye
Verified email at reading.ac.uk
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Year
Platelet signaling: a complex interplay between inhibitory and activatory networks
AP Bye, AJ Unsworth, JM Gibbins
Journal of Thrombosis and Haemostasis 14 (5), 918-930, 2016
1882016
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib
AP Bye, AJ Unsworth, MJ Desborough, CAT Hildyard, N Appleby, D Bruce, ...
Blood advances 1 (26), 2610-2623, 2017
1232017
Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen
AP Bye, AJ Unsworth, S Vaiyapuri, AR Stainer, MJ Fry, JM Gibbins
Arteriosclerosis, thrombosis, and vascular biology 35 (11), 2326-2335, 2015
1082015
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis
S Vaiyapuri, CI Jones, P Sasikumar, LA Moraes, SJ Munger, JR Wright, ...
Circulation 125 (20), 2479-2491, 2012
952012
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets
AP Bye, W Hoepel, JL Mitchell, S Jégouic, S Loureiro, T Sage, ...
Blood, The Journal of the American Society of Hematology 138 (16), 1481-1489, 2021
822021
The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects
AR Stainer, P Sasikumar, AP Bye, AJ Unsworth, LM Holbrook, M Tindall, ...
Th Open 3 (03), e244-e258, 2019
522019
RXR ligands negatively regulate thrombosis and hemostasis
AJ Unsworth, GD Flora, P Sasikumar, AP Bye, T Sage, N Kriek, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (5), 812-822, 2017
362017
Optimizing platelet GPVI inhibition versus haemostatic impairment by the Btk inhibitors ibrutinib, acalabrutinib, ONO/GS-4059, BGB-3111 and evobrutinib
V Denzinger, K Busygina, J Jamasbi, I Pekrul, M Spannagl, C Weber, ...
Thrombosis and Haemostasis 119 (03), 397-406, 2019
352019
Farnesoid X receptor and its ligands inhibit the function of platelets
LA Moraes, AJ Unsworth, S Vaiyapuri, MS Ali, P Sasikumar, T Sage, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2324-2333, 2016
322016
PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity
AJ Unsworth, N Kriek, AP Bye, K Naran, T Sage, GD Flora, JM Gibbins
Journal of Thrombosis and Haemostasis 15 (2), 356-369, 2017
312017
The direct thrombin inhibitors dabigatran and lepirudin inhibit GPIbα-mediated platelet aggregation
K Trabold, S Makhoul, S Gambaryan, J van Ryn, U Walter, K Jurk
Thrombosis and haemostasis 119 (06), 916-929, 2019
232019
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
P Sasikumar, KS AlOuda, WJ Kaiser, LM Holbrook, N Kriek, AJ Unsworth, ...
Journal of thrombosis and haemostasis 16 (5), 946-959, 2018
232018
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation
JL Dunster, AJ Unsworth, AP Bye, EJ Haining, MA Sowa, Y Di, T Sage, ...
Journal of Thrombosis and Haemostasis 18 (2), 485-496, 2020
192020
Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets
AJ Unsworth, AP Bye, DS Tannetta, MJR Desborough, N Kriek, T Sage, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1482-1493, 2017
192017
Multiparameter phenotyping of platelet reactivity for stratification of human cohorts
JL Dunster, AP Bye, N Kriek, T Sage, JL Mitchell, C Kempster, J Batista, ...
Blood advances 5 (20), 4017-4030, 2021
182021
Ca2+ waves coordinate purinergic receptor–evoked integrin activation and polarization
AP Bye, JM Gibbins, MP Mahaut-Smith
Science Signaling 13 (615), eaav7354, 2020
142020
1, 8-Cineole affects agonists-induced platelet activation, thrombus formation and haemostasis
KA Alatawi, D Ravishankar, PH Patra, AP Bye, AR Stainer, K Patel, ...
Cells 10 (10), 2616, 2021
112021
Structural, functional, and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets
KA Sahli, GD Flora, P Sasikumar, AH Maghrabi, LM Holbrook, SK AlOuda, ...
Blood, The Journal of the American Society of Hematology 137 (6), 830-843, 2021
112021
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring
RS Gaspar, AJ Unsworth, A Al-Dibouni, AP Bye, T Sage, M Stewart, ...
Scientific reports 11 (1), 1473, 2021
92021
Spectrum of nonepileptic paroxysmal events in children from Southern India
VK Gowda, R Amoghimath, N Benakappa, SK Shivappa
Journal of Neurosciences in Rural Practice 10 (04), 608-612, 2019
92019
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