|Genome-scale RNAi screen for host factors required for HIV replication|
H Zhou, M Xu, Q Huang, AT Gates, XD Zhang, JC Castle, E Stec, M Ferrer, ...
Cell host & microbe 4 (5), 495-504, 2008
|Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma|
Y Yang, AL Shaffer III, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer cell 21 (6), 723-737, 2012
|High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells|
LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ...
Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014
|MCOLN1 is a ROS sensor in lysosomes that regulates autophagy|
X Zhang, X Cheng, L Yu, J Yang, R Calvo, S Patnaik, X Hu, Q Gao, ...
Nature communications 7 (1), 1-12, 2016
|Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors|
A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ...
ACS chemical biology 11 (11), 3214-3225, 2016
|Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides|
JR Maiolo, M Ferrer, EA Ottinger
Biochimica et Biophysica Acta (BBA)-Biomembranes 1712 (2), 161-172, 2005
|A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis|
M Samie, X Wang, X Zhang, A Goschka, X Li, X Cheng, E Gregg, M Azar, ...
Developmental cell 26 (5), 511-524, 2013
|Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements|
M Ferrer, TM Kapoor, T Strassmaier, W Weissenhorn, JJ Skehel, D Oprian, ...
Nature structural biology 6 (10), 953-960, 1999
|Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions|
SR Bartz, Z Zhang, J Burchard, M Imakura, M Martin, A Palmieri, ...
Molecular and cellular biology 26 (24), 9377-9386, 2006
|Inhibition of calcineurin-mediated endocytosis and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid β oligomer-induced synaptic disruption|
WQ Zhao, F Santini, R Breese, D Ross, XD Zhang, DJ Stone, M Ferrer, ...
Journal of Biological Chemistry 285 (10), 7619-7632, 2010
|PAX3–FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain VulnerabilityPAX3–FOXO1 Establishes Super Enhancers and BRD4 Dependency|
BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ...
Cancer Discovery 7 (8), 884-899, 2017
|Median absolute deviation to improve hit selection for genome-scale RNAi screens|
N Chung, XD Zhang, A Kreamer, L Locco, PF Kuan, S Bartz, PS Linsley, ...
Journal of biomolecular screening 13 (2), 149-158, 2008
|Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation|
W Wang, Q Gao, M Yang, X Zhang, LU Yu, M Lawas, X Li, ...
Proceedings of the National Academy of Sciences 112 (11), E1373-E1381, 2015
|Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome|
GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ...
Cancer cell 24 (1), 90-104, 2013
|Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors|
M Ceribelli, PN Kelly, AL Shaffer, GW Wright, W Xiao, Y Yang, ...
Proceedings of the National Academy of Sciences 111 (31), 11365-11370, 2014
|Formation of disulfide bonds in synthetic peptides and proteins|
D Andreu, F Albericio, NA Solé, MC Munson, M Ferrer, G Barany
Peptide synthesis protocols, 91-169, 1994
|High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer|
A Datta, H Kim, L McGee, AE Johnson, S Talwar, J Marugan, N Southall, ...
Scientific reports 8 (1), 1-13, 2018
|New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening|
MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ...
Science signaling 1 (45), ra12-ra12, 2008
|Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy|
HA Kenny, M Lal-Nag, EA White, M Shen, CY Chiang, AK Mitra, Y Zhang, ...
Nature communications 6 (1), 1-11, 2015
|Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection|
S He, B Lin, V Chu, Z Hu, X Hu, J Xiao, AQ Wang, CJ Schweitzer, Q Li, ...
Science translational medicine 7 (282), 282ra49-282ra49, 2015