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Sam Tonddast-Navaei
Sam Tonddast-Navaei
Verified email at gatech.edu - Homepage
Title
Cited by
Cited by
Year
Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs
B Srinivasan*, S Tonddast‐Navaei, A Roy §, H Zhou, J Skolnick
Medicinal research reviews 39 (2), 684-705, 2019
392019
Are protein-protein interfaces special regions on a protein’s surface?
S Tonddast-Navaei, J Skolnick
The Journal of chemical physics 143 (24), 2015
312015
Mechanism of transient binding and release of substrate protein during the allosteric cycle of the p97 nanomachine
S Tonddast-Navaei, G Stan
Journal of the American Chemical Society 135 (39), 14627-14636, 2013
292013
FcαRI binding at the IgA1 CH2–CH3 interface induces long-range conformational changes that are transmitted to the hinge region
MT Posgai, S Tonddast-Navaei, M Jayasinghe, GM Ibrahim, G Stan, ...
Proceedings of the National Academy of Sciences 115 (38), E8882-E8891, 2018
272018
Ligand binding studies, preliminary structure–activity relationship and detailed mechanistic characterization of 1-phenyl-6, 6-dimethyl-1, 3, 5-triazine-2, 4-diamine …
B Srinivasan, S Tonddast-Navaei, J Skolnick
European journal of medicinal chemistry 103, 600-614, 2015
252015
Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants
B Srinivasan, JV Rodrigues, S Tonddast-Navaei, E Shakhnovich, ...
ACS Chemical Biology 12 (7), 1848-1857, 2017
232017
Asymmetric processing of a substrate protein in sequential allosteric cycles of AAA+ nanomachines
AN Kravats, S Tonddast-Navaei, RJ Bucher, G Stan
The Journal of Chemical Physics 139 (12), 2013
212013
Coarse-grained simulations of topology-dependent mechanisms of protein unfolding and translocation mediated by ClpY ATPase nanomachines
AN Kravats, S Tonddast-Navaei, G Stan
PLoS computational biology 12 (1), e1004675, 2016
152016
On the importance of composite protein multiple ligand interactions in protein pockets
S Tonddast‐Navaei, B Srinivasan, J Skolnick
Journal of computational chemistry 38 (15), 1252-1259, 2017
112017
Correction to Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape …
B Srinivasan, JV Rodrigues, S Tonddast-Navaei, E Shakhnovich, ...
ACS Chemical Biology 13 (5), 1407-1407, 2018
52018
Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma
B Srinivasan, S Tonddast-Navaei, J Skolnick
Bioorganic & medicinal chemistry letters 27 (17), 4133-4139, 2017
32017
Mechanism of Substrate Protein Remodeling by Allosteric Motions of AAA+ Nanomachines
S Tonddast-Navaei
University of Cincinnati, 2013
12013
Multiscale Modeling of Protein Unfolding and Translocation by AAA+ Chaperones in the Degradation Pathway
AN Kravats, S Tonddast-Navaei, A Javidialesaadi, G Stan
Biophysical Journal 112 (3), 491a, 2017
2017
Computational Modeling of the FcαRI Receptor Binding in the Fcα Domain of the Human Antibody IgA: Corse-Grained Molecular Dynamics (MD) Methods
M Jayasinghe, MT Posgai, S Tonddast-Navaei, GM Ibrahim, G Stan, ...
Biophysical Journal 108 (2), 378a, 2015
2015
Computational modeling of the Fc αRI receptor binding in the Fc α domain of the human antibody IgA: Normal Modes Analysis (NMA) study
M Jayasinghe, M Posgai, S Tonddast-Navaei, G Ibrahim, G Stan, A Herr, ...
APS March Meeting Abstracts 2014, C1. 333, 2014
2014
Computational studies of protein unfolding and translocation mediated by ATP-driven AAA plus biological nanomachines
G Stan, A Kravats, S Tonddast-Navaei, M Jayasinghe
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011
2011
The Role of Central Pore Residues of p 97/VCP on Substrate Unfolding and Translocation: A Computational Model
S Tonddast-Navaei, G Stan
Journal of Biomolecular Structure and Dynamics 28 (6), 1020-1021, 2011
2011
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Articles 1–17