| Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency RB Kapust, J Tözsér, JD Fox, DE Anderson, S Cherry, TD Copeland, ... Protein engineering 14 (12), 993-1000, 2001 | 906 | 2001 |
| The P1′ specificity of tobacco etch virus protease RB Kapust, J Tözsér, TD Copeland, DS Waugh Biochemical and biophysical research communications 294 (5), 949-955, 2002 | 439 | 2002 |
| Research applications of proteolytic enzymes in molecular biology JA Mótyán, F Tóth, J Tőzsér Biomolecules 3 (4), 923-942, 2013 | 218 | 2013 |
| Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins J Tözsér, I Bláha, TD Copeland, EM Wondrak, S Oroszlan FEBS letters 281 (1-2), 77-80, 1991 | 191 | 1991 |
| Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease T Sperka, J Pitlik, P Bagossi, J Tözsér Bioorganic & medicinal chemistry letters 15 (12), 3086-3090, 2005 | 184 | 2005 |
| Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro S Nallamsetty, RB Kapust, J Tözsér, S Cherry, JE Tropea, TD Copeland, ... Protein expression and purification 38 (1), 108-115, 2004 | 168 | 2004 |
| Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages MM Budai, A Varga, S Milesz, J Tőzsér, S Benkő Molecular immunology 56 (4), 471-479, 2013 | 147 | 2013 |
| Kinetic and modeling studies of S3-S3'subsites of HIV proteinases J Tozser, IT Weber, A Gustchina, I Blaha, TD Copeland, JM Louis, ... Biochemistry 31 (20), 4793-4800, 1992 | 123 | 1992 |
| Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy É Csősz, P Boross, A Csutak, A Berta, F Tóth, S Póliska, Z Török, J Tőzsér Journal of proteomics 75 (7), 2196-2204, 2012 | 118 | 2012 |
| Folded monomer of HIV-1 protease R Ishima, R Ghirlando, J Tözsér, AM Gronenborn, DA Torchia, JM Louis Journal of Biological Chemistry 276 (52), 49110-49116, 2001 | 117 | 2001 |
| Natural compounds as regulators of NLRP3 inflammasome-mediated IL-1β production J Tőzsér, S Benkő Mediators of Inflammation 2016, 2016 | 115 | 2016 |
| Atomic resolution crystal structures of HIV‐1 protease and mutants V82A and I84V with saquinavir Y Tie, AY Kovalevsky, P Boross, YF Wang, AK Ghosh, J Tozser, ... Proteins: Structure, Function, and Bioinformatics 67 (1), 232-242, 2007 | 109 | 2007 |
| Changes in the chemical barrier composition of tears in Alzheimer’s disease reveal potential tear diagnostic biomarkers G Kalló, M Emri, Z Varga, B Ujhelyi, J Tőzsér, A Csutak, É Csősz PLoS One 11 (6), e0158000, 2016 | 105 | 2016 |
| Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites A Fehér, IT Weber, P Bagossi, P Boross, B Mahalingam, JM Louis, ... European journal of biochemistry 269 (16), 4114-4120, 2002 | 96 | 2002 |
| HIV-I protease: Maturation, enzyme specificity, and drug resistance JM Louis, IT Webert, J Tözsér, GM Clore, AM Gronenborn Advances in pharmacology 49, 111-146, 2000 | 96 | 2000 |
| Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor TD Copeland, EM Wondrak, J Tozser, MM Roberts, S Oroszlan Biochemical and biophysical research communications 169 (1), 310-314, 1990 | 96 | 1990 |
| Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 Ĺ resolution crystal structures of HIV‐1 protease mutants with substrate analogs Y Tie, PI Boross, YF Wang, L Gaddis, F Liu, X Chen, J Tozser, ... The FEBS journal 272 (20), 5265-5277, 2005 | 89 | 2005 |
| Studies on the role of the S4 substrate binding site of HIV proteinases J Tözsér, A Gustchina, IT Weber, I Blaha, EM Wondrak, S Oroszlan FEBS letters 279 (2), 356-360, 1991 | 86 | 1991 |
| Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S F Liu, PI Boross, YF Wang, J Tozser, JM Louis, RW Harrison, IT Weber Journal of molecular biology 354 (4), 789-800, 2005 | 85 | 2005 |
| Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir‐binding site B Mahalingam, YF Wang, PI Boross, J Tozser, JM Louis, RW Harrison, ... European journal of biochemistry 271 (8), 1516-1524, 2004 | 82 | 2004 |
Irene WeberGeorgia State UniversityVerified email at gsu.edu
