Philip Jones
Philip Jones
Wellcome Trust Sanger Institute & Oncology Department, University of Cambridge
Verified email at
Cited by
Cited by
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression
PH Jones, FM Watt
Cell 73 (4), 713-724, 1993
Stem cell patterning and fate in human epidermis
PH Jones, S Harper, FM Watt
Cell 80 (1), 83-93, 1995
A single type of progenitor cell maintains normal epidermis
E Clayton, DP Doupé, AM Klein, DJ Winton, BD Simons, PH Jones
Nature 446 (7132), 185-189, 2007
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature genetics 47 (12), 1402-1407, 2015
Somatic mutant clones colonize the human esophagus with age
I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ...
Science 362 (6417), 911-917, 2018
Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters
S Lowell, P Jones, I Le Roux, J Dunne, FM Watt
Current Biology 10 (9), 491-500, 2000
A single progenitor population switches behavior to maintain and repair esophageal epithelium
DP Doupé, MP Alcolea, A Roshan, G Zhang, AM Klein, BD Simons, ...
Science 337 (6098), 1091-1093, 2012
Developmental cell programs are co-opted in inflammatory skin disease
G Reynolds, P Vegh, J Fletcher, EFM Poyner, E Stephenson, I Goh, ...
Science 371 (6527), eaba6500, 2021
The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate
DP Doupé, AM Klein, BD Simons, PH Jones
Developmental cell 18 (2), 317-323, 2010
Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells
P Jones, G May, L Healy, J Brown, G Hoyne, S Delassus, T Enver
Blood, The Journal of the American Society of Hematology 92 (5), 1505-1511, 1998
Sic transit gloria: farewell to the epidermal transit amplifying cell?
PH Jones, BD Simons, FM Watt
Cell stem cell 1 (4), 371-381, 2007
Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change
MP Alcolea, P Greulich, A Wabik, J Frede, BD Simons, PH Jones
Nature cell biology 16 (6), 612-619, 2014
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study
MR Albertella, PM Loadman, PH Jones, RM Phillips, R Rampling, ...
Clinical cancer research 14 (4), 1096-1104, 2008
Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells
V Zecchini, R Domaschenz, D Winton, P Jones
Genes & development 19 (14), 1686-1691, 2005
Expression and function of the keratinocyte integrins
FM Watt, PH Jones
Development 119 (Supplement), 185-192, 1993
Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia
AM Klein, DE Brash, PH Jones, BD Simons
Proceedings of the National Academy of Sciences 107 (1), 270-275, 2010
Role for amplification and expression of glypican-5 in rhabdomyosarcoma
D Williamson, J Selfe, T Gordon, YJ Lu, K Pritchard-Jones, K Murai, ...
Cancer research 67 (1), 57-65, 2007
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ...
Nature genetics 52 (6), 604-614, 2020
Functional significance of CD9 association with β1 integrins in human epidermal keratinocytes
PH Jones, LA Bishop, FM Watt
Cell adhesion and communication 4 (4-5), 297-305, 1996
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