Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ... Nature medicine 26 (3), 354-359, 2020 | 245 | 2020 |
Visual acuity after retinal gene therapy for choroideremia TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... New England Journal of Medicine 374 (20), 1996-1998, 2016 | 224 | 2016 |
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2−/− ung−/− mice K Xue, C Rada, MS Neuberger The Journal of experimental medicine 203 (9), 2085-2094, 2006 | 208 | 2006 |
First-in-human study of the safety and viability of intraocular robotic surgery TL Edwards, K Xue, HCM Meenink, MJ Beelen, GJL Naus, MP Simunovic, ... Nature biomedical engineering 2 (9), 649-656, 2018 | 190 | 2018 |
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ... Nature medicine 24 (10), 1507-1512, 2018 | 176 | 2018 |
Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa TL Edwards, CL Cottriall, K Xue, MP Simunovic, JD Ramsden, E Zrenner, ... Ophthalmology 125 (3), 432-443, 2018 | 175 | 2018 |
Technique of retinal gene therapy: delivery of viral vector into the subretinal space K Xue, M Groppe, AP Salvetti, RE MacLaren Eye 31 (9), 1308-1316, 2017 | 165 | 2017 |
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1 SG Conticello, K Ganesh, K Xue, M Lu, C Rada, MS Neuberger Molecular cell 31 (4), 474-484, 2008 | 164 | 2008 |
Deep-learning models for the detection and incidence prediction of chronic kidney disease and type 2 diabetes from retinal fundus images K Zhang, X Liu, J Xu, J Yuan, W Cai, T Chen, K Wang, Y Gao, S Nie, X Xu, ... Nature biomedical engineering 5 (6), 533-545, 2021 | 149 | 2021 |
Current status and future trends of clinical diagnoses via image-based deep learning J Xu, K Xue, K Zhang Theranostics 9 (25), 7556, 2019 | 90 | 2019 |
Characterizing the natural history of visual function in choroideremia using microperimetry and multimodal retinal imaging JK Jolly, K Xue, TL Edwards, M Groppe, RE MacLaren Investigative ophthalmology & visual science 58 (12), 5575-5583, 2017 | 85 | 2017 |
The spectrum of CHM gene mutations in choroideremia and their relationship to clinical phenotype MP Simunovic, JK Jolly, K Xue, TL Edwards, M Groppe, SM Downes, ... Investigative ophthalmology & visual science 57 (14), 6033-6039, 2016 | 80 | 2016 |
Correlation of optical coherence tomography and autofluorescence in the outer retina and choroid of patients with choroideremia K Xue, M Oldani, JK Jolly, TL Edwards, M Groppe, SM Downes, ... Investigative Ophthalmology & Visual Science 57 (8), 3674-3684, 2016 | 80 | 2016 |
Antisense oligonucleotide therapeutics in clinical trials for the treatment of inherited retinal diseases K Xue, RE MacLaren Expert Opinion on Investigational Drugs 29 (10), 1163-1170, 2020 | 54 | 2020 |
A deep-learning system predicts glaucoma incidence and progression using retinal photographs F Li, Y Su, F Lin, Z Li, Y Song, S Nie, J Xu, L Chen, S Chen, H Li, K Xue, ... The Journal of Clinical Investigation 132 (11), 2022 | 51 | 2022 |
Structural and functional recovery following limited iatrogenic macular detachment for retinal gene therapy MP Simunovic, K Xue, JK Jolly, RE MacLaren JAMA ophthalmology 135 (3), 234-241, 2017 | 47 | 2017 |
Meta-analysis of the adjunctive use of mitomycin C in primary and revision, external and endonasal dacryocystorhinostomy K Xue, FE Mellington, JH Norris Orbit 33 (4), 239-244, 2014 | 45 | 2014 |
Deep periocular infantile capillary hemangiomas responding to topical application of timolol maleate, 0.5%, drops K Xue, GD Hildebrand JAMA ophthalmology 131 (9), 1246-1248, 2013 | 40 | 2013 |
Immunomodulatory effects of hydroxychloroquine and chloroquine in viral infections and their potential application in retinal gene therapy LC Chandler, IH Yusuf, ME McClements, AR Barnard, RE MacLaren, ... International journal of molecular sciences 21 (14), 4972, 2020 | 38 | 2020 |
Retinal degeneration in choroideremia follows an exponential decay function JW Aylward, K Xue, JK Jolly, JC Wood, J Brett, K Jasani, RE MacLaren Investigative Ophthalmology & Visual Science 59 (9), 6060-6060, 2018 | 37 | 2018 |