Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans CME Remie, KHM Roumans, MPB Moonen, NJ Connell, B Havekes, ... The American journal of clinical nutrition 112 (2), 413-426, 2020 | 132 | 2020 |
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins SD Tyrkalska, S Candel, D Angosto, V Gómez-Abellán, F Martín-Sánchez, ... Nature communications 7 (1), 12077, 2016 | 119 | 2016 |
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor J Giroud-Gerbetant, M Joffraud, MP Giner, A Cercillieux, S Bartova, ... Molecular metabolism 30, 192-202, 2019 | 118 | 2019 |
NAD+ homeostasis in human health and disease R Zapata‐Pérez, RJA Wanders, CDM van Karnebeek, RH Houtkooper EMBO molecular medicine 13 (7), e13943, 2021 | 113 | 2021 |
A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome IA Chatzispyrou, M Alders, S Guerrero-Castillo, R Zapata Perez, ... Human molecular genetics 26 (13), 2541-2550, 2017 | 64 | 2017 |
Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice R Zapata‐Pérez, A Tammaro, BV Schomakers, AML Scantlebery, S Denis, ... The FASEB Journal 35 (4), e21456, 2021 | 53 | 2021 |
Healthy aging and muscle function are positively associated with NAD+ abundance in humans GE Janssens, L Grevendonk, RZ Perez, BV Schomakers, ... Nature Aging 2 (3), 254-263, 2022 | 46 | 2022 |
NAD+-precursor supplementation with L-tryptophan, nicotinic acid, and nicotinamide does not affect mitochondrial function or skeletal muscle function in physically compromised … NJ Connell, L Grevendonk, CE Fealy, E Moonen-Kornips, YMH Bruls, ... The Journal of Nutrition 151 (10), 2917-2931, 2021 | 20 | 2021 |
Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis R Zapata-Pérez, F Gil-Ortiz, AB Martínez-Moñino, AG García-Saura, ... Open biology 7 (4), 160327, 2017 | 19 | 2017 |
Biochemical and Mutational Analysis of a Novel Nicotinamidase from Oceanobacillus iheyensis HTE831 G Sánchez-Carrón, MI García-García, R Zapata-Pérez, H Takami, ... PLoS One 8 (2), e56727, 2013 | 18 | 2013 |
A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA JT Cánovas-Márquez, S Falk, FE Nicolás, S Padmanabhan, ... Nucleic Acids Research 49 (9), 5294-5307, 2021 | 9 | 2021 |
Comparative inhibitory profile and distribution of bacterial PARPs, using Clostridioides difficile CD160 PARP as a model AG García-Saura, R Zapata-Pérez, JF Hidalgo, Á Sánchez-Ferrer Scientific Reports 8 (1), 8056, 2018 | 8 | 2018 |
The female mouse is resistant to mild vitamin B3 deficiency I van der Stelt, W Shi, M Bekkenkamp-Grovenstein, R Zapata-Pérez, ... European Journal of Nutrition 61 (1), 329-340, 2022 | 7 | 2022 |
NAD+ homeostasis in human health and disease. EMBO Mol Med 13 (7): e13943 R Zapata-Pérez, RJA Wanders, CDM van Karnebeek, RH Houtkooper | 7 | 2021 |
Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and … AB Martínez-Moñino, R Zapata-Pérez, AG García-Saura, F Gil-Ortiz, ... PloS one 12 (4), e0174759, 2017 | 7 | 2017 |
Combined whole-cell high-throughput functional screening for identification of new nicotinamidases/pyrazinamidases in metagenomic/polygenomic libraries R Zapata-Pérez, AG García-Saura, M Jebbar, PN Golyshin, ... Frontiers in Microbiology 7, 228391, 2016 | 7 | 2016 |
Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome D Damschroder, R Zapata-Pérez, K Richardson, FM Vaz, RH Houtkooper, ... Disease models & mechanisms 15 (10), dmm049279, 2022 | 6 | 2022 |
An uncharacterized FMAG_01619 protein from Fusobacterium mortiferum ATCC 9817 demonstrates that some bacterial macrodomains can also act as poly-ADP … AG García-Saura, R Zapata-Pérez, JF Hidalgo, J Cabanes, F Gil-Ortiz, ... Scientific Reports 9 (1), 3230, 2019 | 6 | 2019 |
A reduced form of nicotinamide riboside defines a new path for NAD (+) biosynthesis and acts as an orally bioavailable NAD (+) precursor. Mol Metab 30: 192–202 J Giroud-Gerbetant, M Joffraud, MP Giner, A Cercillieux, S Bartova, ... Mech Ageing Dev 198 (111545), 84, 2019 | 6 | 2019 |
A new cross-linked enzyme aggregate biocatalyst for NAD+-booster production AB Martínez-Moñino, R Zapata-Pérez, AG García-Saura, J Cabanes, ... RSC advances 7 (23), 14272-14278, 2017 | 5 | 2017 |