| Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice RJ Ferrante, JK Kubilus, J Lee, H Ryu, A Beesen, B Zucker, K Smith, ... Journal of Neuroscience 23 (28), 9418-9427, 2003 | 845 | 2003 |
| GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease S Jo, O Yarishkin, YJ Hwang, YE Chun, M Park, DH Woo, JY Bae, T Kim, ... Nature medicine 20 (8), 886-896, 2014 | 744 | 2014 |
| Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease G Gardian, SE Browne, DK Choi, P Klivenyi, J Gregorio, JK Kubilus, ... Journal of Biological Chemistry 280 (1), 556-563, 2005 | 522 | 2005 |
| Sodium phenylbutyrate prolongs survival and regulates expression of anti‐apoptotic genes in transgenic amyotrophic lateral sclerosis mice H Ryu, K Smith, SI Camelo, I Carreras, J Lee, AH Iglesias, F Dangond, ... Journal of neurochemistry 93 (5), 1087-1098, 2005 | 440 | 2005 |
| Protection from oxidative stress–induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced dna binding of hypoxia-inducible factor-1 and atf … K Zaman, H Ryu, D Hall, K O'Donovan, KI Lin, MP Miller, JC Marquis, ... Journal of Neuroscience 19 (22), 9821-9830, 1999 | 435 | 1999 |
| Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox J Lee, H Ryu, RJ Ferrante, SM Morris Jr, RR Ratan Proceedings of the National Academy of Sciences 100 (8), 4843-4848, 2003 | 431 | 2003 |
| Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration S Khanna, S Roy, H Ryu, P Bahadduri, PW Swaan, RR Ratan, CK Sen Journal of Biological Chemistry 278 (44), 43508-43515, 2003 | 382 | 2003 |
| miR‐206 regulates brain‐derived neurotrophic factor in Alzheimer disease model ST Lee, K Chu, KH Jung, JH Kim, JY Huh, H Yoon, DK Park, JY Lim, ... Annals of neurology 72 (2), 269-277, 2012 | 368 | 2012 |
| ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease H Ryu, J Lee, SW Hagerty, BY Soh, SE McAlpin, KA Cormier, KM Smith, ... Proceedings of the National Academy of Sciences 103 (50), 19176-19181, 2006 | 358 | 2006 |
| Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis S Camelo, AH Iglesias, D Hwang, B Due, H Ryu, K Smith, SG Gray, ... Journal of neuroimmunology 164 (1-2), 10-21, 2005 | 331 | 2005 |
| Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway H Ryu, J Lee, BA Olofsson, A Mwidau, A Deodoglu, M Escudero, ... Proceedings of the National Academy of Sciences 100 (7), 4281-4286, 2003 | 323 | 2003 |
| Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice EC Stack, JK Kubilus, K Smith, K Cormier, SJ Del Signore, E Guelin, ... Journal of Comparative Neurology 490 (4), 354-370, 2005 | 294 | 2005 |
| ASC is a Bax adaptor and regulates the p53–Bax mitochondrial apoptosis pathway T Ohtsuka, H Ryu, YA Minamishima, S Macip, J Sagara, KI Nakayama, ... Nature cell biology 6 (2), 121-128, 2004 | 291 | 2004 |
| Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons H Ryu, J Lee, K Zaman, J Kubilis, RJ Ferrante, BD Ross, R Neve, ... Journal of Neuroscience 23 (9), 3597-3606, 2003 | 288 | 2003 |
| Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice AC McKee, I Carreras, L Hossain, H Ryu, WL Klein, S Oddo, FM LaFerla, ... Brain research 1207, 225-236, 2008 | 260 | 2008 |
| Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival J Lee, CH Kim, DK Simon, LR Aminova, AY Andreyev, YE Kushnareva, ... Journal of Biological Chemistry 280 (49), 40398-40401, 2005 | 227 | 2005 |
| Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease RJ Ferrante, H Ryu, JK Kubilus, S D'Mello, KL Sugars, J Lee, P Lu, ... Journal of Neuroscience 24 (46), 10335-10342, 2004 | 219 | 2004 |
| Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ... Nature neuroscience 23 (12), 1555-1566, 2020 | 203 | 2020 |
| SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease J Lee, Y Kim, T Liu, YJ Hwang, SJ Hyeon, H Im, K Lee, VE Alvarez, ... Aging cell 17 (1), e12679, 2018 | 185 | 2018 |
| Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons H Ryu, J Lee, S Impey, RR Ratan, RJ Ferrante Proceedings of the National Academy of Sciences 102 (39), 13915-13920, 2005 | 177 | 2005 |
