| Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Science 371 (6532), eabc8378, 2021 | 309 | 2021 |
| High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 228* | 2021 |
| Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets AP Bye, W Hoepel, JL Mitchell, S Jégouic, S Loureiro, T Sage, ... Blood, The Journal of the American Society of Hematology 138 (16), 1481-1489, 2021 | 82 | 2021 |
| Serum IgA immune complexes promote proinflammatory cytokine production by human macrophages, monocytes, and Kupffer cells through FcαRI–TLR cross-talk IS Hansen, W Hoepel, SAJ Zaat, DLP Baeten, J den Dunnen The Journal of Immunology 199 (12), 4124-4131, 2017 | 71 | 2017 |
| FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming IS Hansen, L Krabbendam, JH Bernink, F Loayza-Puch, W Hoepel, ... Nature communications 9 (1), 863, 2018 | 51 | 2018 |
| C-reactive protein promotes inflammation through FcγR-induced glycolytic reprogramming of human macrophages M Newling, L Sritharan, AJ van der Ham, W Hoepel, RH Fiechter, ... The Journal of Immunology 203 (1), 225-235, 2019 | 38 | 2019 |
| FcγR-TLR cross-talk enhances TNF production by human monocyte-derived DCs via IRF5-dependent gene transcription and glycolytic reprogramming W Hoepel, M Newling, LTC Vogelpoel, L Sritharan, IS Hansen, ... Frontiers in immunology 10, 739, 2019 | 34 | 2019 |
| IgG subclasses shape cytokine responses by human myeloid immune cells through differential metabolic reprogramming W Hoepel, S Allahverdiyeva, H Harbiye, SW de Taeye, AJ van der Ham, ... The Journal of Immunology 205 (12), 3400-3407, 2020 | 23 | 2020 |
| FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4 K Golebski, W Hoepel, D Van Egmond, EJ De Groot, GD Amatngalim, ... Mucosal immunology 12 (2), 425-433, 2019 | 22 | 2019 |
| Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells M Newling, W Hoepel, LTC Vogelpoel, MH Heineke, JA van Burgsteden, ... European journal of immunology 48 (11), 1796-1809, 2018 | 22 | 2018 |
| The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees J Van Coillie, T Pongracz, J Rahmöller, HJ Chen, CE Geyer, ... EBioMedicine 87, 2023 | 21 | 2023 |
| IgG immune complexes break immune tolerance of human microglia M van der Poel, W Hoepel, J Hamann, I Huitinga, J Dunnen The Journal of Immunology 205 (9), 2511-2518, 2020 | 21 | 2020 |
| Physiological and pathological inflammation induced by antibodies and pentraxins CE Geyer, L Mes, M Newling, J den Dunnen, W Hoepel Cells 10 (5), 1175, 2021 | 13 | 2021 |
| Dysregulated Fcγ receptor IIa-induced cytokine production in dendritic cells of lupus nephritis patients M Newling, RH Fiechter, L Sritharan, W Hoepel, JA van Burgsteden, ... Clinical & Experimental Immunology 199 (1), 39-49, 2020 | 10 | 2020 |
| COVID-19, biobank study group MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Rispens, T, 2021 | 9* | 2021 |
| Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies W Hoepel, K Golebski, CM van Drunen, J den Dunnen Journal of Allergy and Clinical Immunology 146 (2), 273-275, 2020 | 9 | 2020 |
| Multiple sclerosis: why we should focus on both sides of the (auto) antibody J Den Dunnen, L Mes, W Hoepel, J Smolders Neural Regeneration Research 16 (12), 2422-2424, 2021 | 6 | 2021 |
| IgA2 immune complexes selectively promote inflammation by human CD103+ dendritic cells L Mes, U Steffen, HJ Chen, J Veth, W Hoepel, GR Griffith, G Schett, ... Frontiers in immunology 14, 1116435, 2023 | 4 | 2023 |
| Amsterdam UMC COVID-19; Biobank Study Group, Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Science 371, 2021 | 3 | 2021 |
| Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19 CE Geyer, HJ Chen, AP Bye, XD Manz, D Guerra, TG Caniels, TPL Bijl, ... Life Science Alliance 6 (11), 2023 | 2 | 2023 |
