| Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning C Kellendonk, EH Simpson, HJ Polan, G Malleret, S Vronskaya, V Winiger, ... Neuron 49 (4), 603-615, 2006 | 619 | 2006 |
| A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia EH Simpson, C Kellendonk, E Kandel Neuron 65 (5), 585-596, 2010 | 538 | 2010 |
| Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors YY Huang, E Simpson, C Kellendonk, ER Kandel Proceedings of the National Academy of Sciences 101 (9), 3236-3241, 2004 | 276 | 2004 |
| Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing MR Drew, EH Simpson, C Kellendonk, WG Herzberg, O Lipatova, ... Journal of Neuroscience 27 (29), 7731-7739, 2007 | 240 | 2007 |
| COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C] NNC112 and PET M Slifstein, B Kolachana, EH Simpson, P Tabares, B Cheng, M Duvall, ... Molecular psychiatry 13 (8), 821-827, 2008 | 233 | 2008 |
| Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation P Trifilieff, B Feng, E Urizar, V Winiger, RD Ward, KM Taylor, D Martinez, ... Molecular psychiatry 18 (9), 1025, 2013 | 232 | 2013 |
| The behavioral neuroscience of motivation: an overview of concepts, measures, and translational applications EH Simpson, PD Balsam Behavioral neuroscience of motivation, 1-12, 2016 | 171 | 2016 |
| Modeling cognitive endophenotypes of schizophrenia in mice C Kellendonk, EH Simpson, ER Kandel Trends in neurosciences 32 (6), 347-358, 2009 | 160 | 2009 |
| Neural substrates underlying effort, time, and risk-based decision making in motivated behavior MR Bailey, EH Simpson, PD Balsam Neurobiology of Learning and Memory 133, 233-256, 2016 | 122 | 2016 |
| DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability H Xu, CB Kellendonk, EH Simpson, JG Keilp, GE Bruder, HJ Polan, ... Schizophrenia research 90 (1-3), 104-107, 2007 | 119 | 2007 |
| Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia RD Ward, EH Simpson, VL Richards, G Deo, K Taylor, JI Glendinning, ... Neuropsychopharmacology 37 (7), 1699-1707, 2012 | 113 | 2012 |
| Using conditional mutagenesis to study the brain A Morozov, C Kellendonk, E Simpson, F Tronche Biological psychiatry 54 (11), 1125-1133, 2003 | 97 | 2003 |
| Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia EH Simpson, C Kellendonk, RD Ward, V Richards, O Lipatova, S Fairhurst, ... Biological psychiatry 69 (10), 928-935, 2011 | 96 | 2011 |
| Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits. RD Ward, C Kellendonk, EH Simpson, O Lipatova, MR Drew, S Fairhurst, ... Behavioral neuroscience 123 (4), 720, 2009 | 95 | 2009 |
| D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex YC Li, C Kellendonk, EH Simpson, ER Kandel, WJ Gao Proceedings of the National Academy of Sciences 108 (29), 12107-12112, 2011 | 86 | 2011 |
| Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning ME Bach, EH Simpson, L Kahn, JJ Marshall, ER Kandel, C Kellendonk Proceedings of the National Academy of Sciences 105 (41), 16027-16032, 2008 | 74 | 2008 |
| Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area S Krabbe, J Duda, J Schiemann, C Poetschke, G Schneider, ER Kandel, ... Proceedings of the National Academy of Sciences 112 (12), E1498-E1506, 2015 | 68 | 2015 |
| Schizophrenia in translation: dissecting motivation in schizophrenia and rodents EH Simpson, JA Waltz, C Kellendonk, PD Balsam Schizophrenia bulletin 38 (6), 1111-1117, 2012 | 68 | 2012 |
| The mouse Cer1 (Cerberus related or homologue) gene is not required for anterior pattern formation EH Simpson, DK Johnson, P Hunsicker, R Suffolk, SA Jordan, IJ Jackson Developmental Biology 213 (1), 202-206, 1999 | 67 | 1999 |
| Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition EH Simpson, V Winiger, DK Biezonski, I Haq, ER Kandel, C Kellendonk Biological psychiatry 76 (10), 823-831, 2014 | 59 | 2014 |
Peter BalsamProfessor of Psychology Barnard College and Columbia UniversityVerified email at columbia.edu
