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David Savitsky
David Savitsky
Associate Director
Verified email at agenusbio.com
Title
Cited by
Cited by
Year
The IRF family transcription factors in immunity and oncogenesis
T Tamura, H Yanai, D Savitsky, T Taniguchi
Annu. Rev. Immunol. 26, 535-584, 2008
12092008
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
H Yanai, T Ban, ZC Wang, MK Choi, T Kawamura, H Negishi, M Nakasato, ...
Nature 462 (7269), 99-103, 2009
6982009
Regulation of immunity and oncogenesis by the IRF transcription factor family
D Savitsky, T Tamura, H Yanai, T Taniguchi
Cancer immunology, immunotherapy 59 (4), 489-510, 2010
2972010
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
M Shapiro-Shelef, KI Lin, D Savitsky, J Liao, K Calame
The Journal of experimental medicine 202 (11), 1471-1476, 2005
2622005
Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1
E Magnúsdóttir, S Kalachikov, K Mizukoshi, D Savitsky, ...
Proceedings of the National Academy of Sciences 104 (38), 14988-14993, 2007
1732007
A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA
MK Choi, ZC Wang, T Ban, H Yanai, Y Lu, R Koshiba, Y Nakaima, ...
Proceedings of the National Academy of Sciences 106 (42), 17870-17875, 2009
1362009
B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion
D Savitsky, K Calame
The Journal of experimental medicine 203 (10), 2305-2314, 2006
1222006
Regulation of the cytosolic DNA-sensing system in innate immunity: a current view
H Yanai, D Savitsky, T Tamura, T Taniguchi
Current opinion in immunology 21 (1), 17-22, 2009
892009
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus
DA Savitsky, H Yanai, T Tamura, T Taniguchi, K Honda
Proceedings of the National Academy of Sciences 107 (22), 10154-10159, 2010
882010
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens
JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ...
Cancer Cell 33 (6), 1033-1047. e5, 2018
462018
Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1
CA Lord, D Savitsky, R Sitcheran, K Calame, JR Wright, JPY Ting, ...
The Journal of Immunology 182 (5), 2948-2958, 2009
342009
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody
RB Gombos, A Gonzalez, M Manrique, D Chand, D Savitsky, B Morin, ...
PLoS One 13 (4), e0191926, 2018
162018
Multiple roles for Blimp-1 in B and T lymphocytes
D Savitsky, L Cimmino, T Kuo, GA Martins, K Calame
Mechanisms of Lymphocyte Activation and Immune Regulation XI, 9-30, 2007
162007
Anti-OX40 antibodies
M Van Dijk, EV Breous-Nystrom, G Ritter, D Schaer, ...
US Patent 10,259,882, 2019
152019
INCAGN02385 is an antagonist antibody targeting the co-inhibitory receptor LAG-3 for the treatment of human malignancies
D Savitsky, R Ward, C Riordan, C Mundt, S Jennings, J Connolly, ...
Cancer research 78 (13_Supplement), 3819-3819, 2018
142018
Anti-PD-1 antibodies and methods of use thereof
M Van Dijk, NS Wilson, CA Mundt, G Ritter, JD Wolchok, T Merghoub, ...
US Patent 10,323,091, 2019
112019
A novel agonist antibody (INCAGN01876) that targets the costimulatory receptor GITR
AM Gonzalez, E Breous, ML Manrique, D Savitsky, J Waight, R Gombos, ...
Cancer Research 76 (14_Supplement), 3220-3220, 2016
102016
Anti-CTLA-4 antibodies and methods of use thereof
M Van Dijk, CA Mundt, G Ritter, D Schaer, JD Wolchok, T Merghoub, ...
US Patent 10,144,779, 2018
92018
Phase I/II, open-label, multiple ascending dose trial of AGEN2034, an anti–PD-1 monoclonal antibody, in advanced solid malignancies: results of dose escalation in advanced …
C Drescher, KN Moore, JF Liu, DM O’Malley, EW Wang, JSZ Wang, ...
Annals of Oncology 29, viii412-viii413, 2018
72018
Phase 1/2 open-label, multiple ascending dose trial of AGEN2034, an anti-PD-1 monoclonal antibody, in advanced solid malignancies: Results of dose escalation.
KN Moore, C Dresher, J Liu, DM O'Malley, EW Wang, JSZ Wang, ...
Journal of Clinical Oncology 36 (15_suppl), 3086-3086, 2018
52018
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