Global profiling of co- and post-translationally N-myristoylated proteomes in human cells E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ... Nature communications 5 (1), 4919, 2014 | 243 | 2014 |
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ... Nature chemistry 6 (2), 112-121, 2014 | 213 | 2014 |
Chemoselective Staudinger‐phosphite reaction of azides for the phosphorylation of proteins R Serwa, I Wilkening, G Del Signore, M Mühlberg, I Claußnitzer, C Weise, ... Angewandte Chemie International Edition 48 (44), 8234-8239, 2009 | 173 | 2009 |
Dynamic protein acylation: new substrates, mechanisms, and drug targets T Lanyon-Hogg, M Faronato, RA Serwa, EW Tate Trends in biochemical sciences 42 (7), 566-581, 2017 | 129 | 2017 |
Synthesis and reactivity of some 6-substituted-2, 4-dimethyl-3-pyridinols, a novel class of chain-breaking antioxidants M Wijtmans, DA Pratt, J Brinkhorst, R Serwa, L Valgimigli, GF Pedulli, ... The Journal of Organic Chemistry 69 (26), 9215-9223, 2004 | 117 | 2004 |
Site-specifically phosphorylated lysine peptides J Bertran-Vicente, RA Serwa, M Schümann, P Schmieder, E Krause, ... Journal of the American Chemical Society 136 (39), 13622-13628, 2014 | 97 | 2014 |
Site-specific PEGylation of proteins by a Staudinger-phosphite reaction R Serwa, P Majkut, B Horstmann, JM Swiecicki, M Gerrits, E Krause, ... Chemical Science 1 (5), 596-602, 2010 | 96 | 2010 |
Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics EM Storck, J Morales-Sanfrutos, RA Serwa, N Panyain, T Lanyon-Hogg, ... Nature Chemistry 11 (6), 552-561, 2019 | 95 | 2019 |
Multifunctional reagents for quantitative proteome‐wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development M Broncel, RA Serwa, P Ciepla, E Krause, MJ Dallman, AI Magee, ... Angewandte Chemie International Edition 54 (20), 5948-5951, 2015 | 91 | 2015 |
Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani MH Wright, D Paape, EM Storck, RA Serwa, DF Smith, EW Tate Chemistry & biology 22 (3), 342-354, 2015 | 89 | 2015 |
A fluorescence-based assay for N-myristoyltransferase activity V Goncalves, JA Brannigan, E Thinon, TO Olaleye, R Serwa, S Lanzarone, ... Analytical biochemistry 421 (1), 342-344, 2012 | 85 | 2012 |
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis WD Hong, F Benayoud, GL Nixon, L Ford, KL Johnston, RH Clare, ... Proceedings of the National Academy of Sciences 116 (4), 1414-1419, 2019 | 68 | 2019 |
Global profiling of Huntingtin-associated protein E (HYPE)-mediated AMPylation through a chemical proteomic approach M Broncel, RA Serwa, TD Bunney, M Katan, EW Tate Molecular & Cellular Proteomics 15 (2), 715-725, 2016 | 63 | 2016 |
Preparation and Investigation of Vitamin B6‐Derived Aminopyridinol Antioxidants R Serwa, T Nam, L Valgimigli, S Culbertson, CL Rector, BS Jeong, ... Chemistry–A European Journal 16 (47), 14106-14114, 2010 | 61 | 2010 |
Systems analysis of protein fatty acylation in herpes simplex virus-infected cells using chemical proteomics RA Serwa, F Abaitua, E Krause, EW Tate, P O’Hare Chemistry & biology 22 (8), 1008-1017, 2015 | 57 | 2015 |
Site-specific functionalisation of proteins by a Staudinger-type reaction using unsymmetrical phosphites V Böhrsch, R Serwa, P Majkut, E Krause, CPR Hackenberger Chemical communications 46 (18), 3176-3178, 2010 | 57 | 2010 |
Stabilization of peptides for intracellular applications by phosphoramidate-linked polyethylene glycol chains N Nischan, A Chakrabarti, RA Serwa, PH Bovee-Geurts, R Brock, ... Angew Chem Int Ed Engl 52 (45), 11920-11924, 2013 | 52 | 2013 |
Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry SB Milne, KA Tallman, R Serwa, CA Rouzer, MD Armstrong, LJ Marnett, ... Nature chemical biology 6 (3), 205-207, 2010 | 48 | 2010 |
Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation D Alibhai, DJ Kelly, S Warren, S Kumar, A Margineau, RA Serwa, ... Journal of biophotonics 6 (5), 398-408, 2013 | 46 | 2013 |
New chemical probes targeting cholesterylation of Sonic Hedgehog in human cells and zebrafish P Ciepla, AD Konitsiotis, RA Serwa, N Masumoto, WP Leong, MJ Dallman, ... Chemical science 5 (11), 4249-4259, 2014 | 44 | 2014 |