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Benjamin Cravatt
Benjamin Cravatt
Professor of Chemistry, The Scripps Research Institute
Verified email at scripps.edu
Title
Cited by
Cited by
Year
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
BF Cravatt, DK Giang, SP Mayfield, DL Boger, RA Lerner, NB Gilula
Nature 384 (6604), 83-87, 1996
25641996
Quantitative reactivity profiling predicts functional cysteines in proteomes
E Weerapana, C Wang, GM Simon, F Richter, S Khare, MBD Dillon, ...
Nature 468 (7325), 790-795, 2010
15812010
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
BF Cravatt, K Demarest, MP Patricelli, MH Bracey, DK Giang, BR Martin, ...
Proceedings of the National Academy of Sciences 98 (16), 9371-9376, 2001
15192001
Activity-based protein profiling: from enzyme chemistry to proteomic chemistry
BF Cravatt, AT Wright, JW Kozarich
Annu. Rev. Biochem. 77, 383-414, 2008
13732008
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
JL Blankman, GM Simon, BF Cravatt
Chemistry & biology 14 (12), 1347-1356, 2007
13262007
Activity-based protein profiling: the serine hydrolases
Y Liu, MP Patricelli, BF Cravatt
Proceedings of the National Academy of Sciences 96 (26), 14694-14699, 1999
13121999
Activity-based protein profiling in vivo using a copper (I)-catalyzed azide-alkyne [3+ 2] cycloaddition
AE Speers, GC Adam, BF Cravatt
Journal of the American Chemical Society 125 (16), 4686-4687, 2003
12882003
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
LJ Macpherson, AE Dubin, MJ Evans, F Marr, PG Schultz, BF Cravatt, ...
Nature 445 (7127), 541-545, 2007
12872007
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
DK Nomura, JZ Long, S Niessen, HS Hoover, SW Ng, BF Cravatt
Cell 140 (1), 49-61, 2010
10812010
Profiling enzyme activities in vivo using click chemistry methods
AE Speers, BF Cravatt
Chemistry & biology 11 (4), 535-546, 2004
10372004
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
JZ Long, W Li, L Booker, JJ Burston, SG Kinsey, JE Schlosburg, FJ Pavón, ...
Nature chemical biology 5 (1), 37-44, 2009
10292009
The biological impact of mass-spectrometry-based proteomics
BF Cravatt, GM Simon, JR Yates Iii
Nature 450 (7172), 991-1000, 2007
8602007
Chemical characterization of a family of brain lipids that induce sleep
BF Cravatt, O Prospero-Garcia, G Siuzdak, NB Gilula, SJ Henriksen, ...
Science 268 (5216), 1506-1509, 1995
7841995
Structure and function of fatty acid amide hydrolase
MK McKinney, BF Cravatt
Annu. Rev. Biochem. 74, 411-432, 2005
7832005
How many human proteoforms are there?
R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ...
Nature chemical biology 14 (3), 206-214, 2018
7732018
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
DK Nomura, BE Morrison, JL Blankman, JZ Long, SG Kinsey, ...
Science 334 (6057), 809-813, 2011
7492011
Proteome-wide covalent ligand discovery in native biological systems
KM Backus, BE Correia, KM Lum, S Forli, BD Horning, GE González-Páez, ...
Nature 534 (7608), 570-574, 2016
7252016
Mechanism-based profiling of enzyme families
MJ Evans, BF Cravatt
Chemical reviews 106 (8), 3279-3301, 2006
7142006
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
JE Schlosburg, JL Blankman, JZ Long, DK Nomura, B Pan, SG Kinsey, ...
Nature neuroscience 13 (9), 1113-1119, 2010
6852010
Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
K Ahn, MK McKinney, BF Cravatt
Chemical reviews 108 (5), 1687-1707, 2008
6352008
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