| Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry S Yang, M Xu, EM Lee, K Gorshkov, SA Shiryaev, S He, W Sun, ... Cell discovery 4 (1), 31, 2018 | 143 | 2018 |
| Drug combination therapy for emerging viral diseases ZA Shyr, YS Cheng, DC Lo, W Zheng Drug discovery today 26 (10), 2367-2376, 2021 | 77 | 2021 |
| The SARS-CoV-2 cytopathic effect is blocked by lysosome alkalizing small molecules K Gorshkov, CZ Chen, R Bostwick, L Rasmussen, BN Tran, YS Cheng, ... ACS infectious diseases 7 (6), 1389-1408, 2020 | 64 | 2020 |
| Improving therapy of severe infections through drug repurposing of synergistic combinations YS Cheng, PR Williamson, W Zheng Current opinion in pharmacology 48, 92-98, 2019 | 62 | 2019 |
| Facilitated unbinding via multivalency-enabled ternary complexes: new paradigm for protein–DNA interactions TY Chen, YS Cheng, PS Huang, P Chen Accounts of chemical research 51 (4), 860-868, 2018 | 44 | 2018 |
| A lysine acetyltransferase contributes to the metabolic adaptation to hypoxia in Mycobacterium tuberculosis ESC Rittershaus, SH Baek, IV Krieger, SJ Nelson, YS Cheng, S Nambi, ... Cell Chemical Biology 25 (12), 1495-1505. e3, 2018 | 39 | 2018 |
| Zika virus-induced neuronal apoptosis via increased mitochondrial fragmentation S Yang, K Gorshkov, EM Lee, M Xu, YS Cheng, N Sun, F Soheilian, ... Frontiers in microbiology 11, 598203, 2020 | 35 | 2020 |
| Repurposing Screen Identifies Unconventional Drugs With Activity Against Multidrug Resistant Acinetobacter baumannii YS Cheng, W Sun, M Xu, M Shen, M Khraiwesh, RJ Sciotti, W Zheng Frontiers in cellular and infection microbiology 8, 438, 2019 | 34 | 2019 |
| Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid … YS Cheng, JC Sacchettini Biochemistry 55 (7), 1107-1119, 2016 | 26 | 2016 |
| Identification of antifungal compounds against multidrug-resistant Candida auris utilizing a high-throughput drug-repurposing screen YS Cheng, JS Roma, M Shen, C Mota Fernandes, PS Tsang, HE Forbes, ... Antimicrobial agents and chemotherapy 65 (4), 10.1128/aac. 01305-20, 2021 | 23 | 2021 |
| Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor S Tang, ND Hicks, YS Cheng, A Silva, SM Fortune, JC Sacchettini Nucleic Acids Research 47 (18), 9934-9949, 2019 | 20 | 2019 |
| Quantifying the oligomeric states of membrane proteins in cells through super-resolution localizations X Xie, YS Cheng, MH Wen, A Calindi, K Yang, CW Chiu, TY Chen The Journal of Physical Chemistry B 122 (46), 10496-10504, 2018 | 10 | 2018 |
| A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p. R854X mutation in the GAA gene YS Cheng, R Li, A Baskfield, J Beers, J Zou, C Liu, W Zheng Stem cell research 37, 101435, 2019 | 9 | 2019 |
| iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II J Hong, YS Cheng, S Yang, M Swaroop, M Xu, J Beers, J Zou, W Huang, ... Experimental cell research 412 (1), 113007, 2022 | 7 | 2022 |
| Modeling CNS involvement in Pompe disease using neural stem cells generated from patient-derived induced pluripotent stem cells YS Cheng, S Yang, J Hong, R Li, J Beers, J Zou, W Huang, W Zheng Cells 10 (1), 8, 2020 | 7 | 2020 |
| Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p. Q208X and p. G310G mutations in the NGLY1 gene R Li, M Pradhan, M Xu, A Baskfield, A Farkhondeh, YS Cheng, J Beers, ... Stem cell research 34, 101362, 2019 | 6 | 2019 |
| Terfenadine resensitizes doxorubicin activity in drug-resistant ovarian cancer cells via an inhibition of CaMKII/CREB1 mediated ABCB1 expression W Huang, S Yang, YS Cheng, N Sima, W Sun, M Shen, JC Braisted, W Lu, ... Frontiers in Oncology 12, 1068443, 2022 | 5 | 2022 |
| Drug repurposing of synergistic drug combinations as an alternative approach for the treatment of severe infectious diseases YS Cheng, PR Williamson, W Zheng Current opinion in pharmacology 48, 92, 2019 | 5 | 2019 |
| Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene J Hong, M Xu, R Li, YS Cheng, J Kouznetsova, J Beers, C Liu, J Zou, ... Stem cell research 37, 101451, 2019 | 5 | 2019 |
| Disease modeling for Mucopolysaccharidosis type IIIB using patient derived induced pluripotent stem cells W Huang, YS Cheng, S Yang, M Swaroop, M Xu, W Huang, W Zheng Experimental cell research 407 (1), 112785, 2021 | 4 | 2021 |
