Marco G. Casteleijn
Marco G. Casteleijn
Research Team Leader (VTT) | Adjunct Prof. (University of Helsinki)
Verified email at - Homepage
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Pharmacokinetic aspects of retinal drug delivery
EM Del Amo, AK Rimpelä, E Heikkinen, OK Kari, E Ramsay, T Lajunen, ...
Progress in retinal and eye research 57, 134-185, 2017
Enzyme controlled glucose auto-delivery for high cell density cultivations in microplates and shake flasks
J Panula-Perälä, J Šiurkus, A Vasala, R Wilmanowski, MG Casteleijn, ...
Microbial cell factories 7 (1), 1-12, 2008
Application of aptamers in diagnostics, drug-delivery and imaging
C Chandola, S Kalme, MG Casteleijn, A Urtti, M Neerathilingam
Journal of Biosciences, 1-27, 2016
Expression without boundaries: cell-free protein synthesis in pharmaceutical research
MG Casteleijn, A Urtti, S Sarkhel
International journal of pharmaceutics 440 (1), 39-47, 2013
Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material
DMAM Luykx, MG Casteleijn, W Jiskoot, J Westdijk, PMJM Jongen
European journal of pharmaceutical sciences 23 (1), 65-75, 2004
Functional Role of the Conserved Active Site Proline of Triosephosphate Isomerase,
MG Casteleijn, M Alahuhta, K Groebel, I El-Sayed, K Augustyns, ...
Biochemistry 45 (51), 15483-15494, 2006
Assessment of recombinant protein production in E. coli with Time-Gated Surface Enhanced Raman Spectroscopy (TG-SERS)
M Kögler, J Itkonen, T Viitala, MG Casteleijn
Scientific Reports 10 (2472), 2020
Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions
MG Casteleijn, D Richardson, P Parkkila, N Granqvist, A Urtti, T Viitala
Colloids and Surfaces A: Physicochemical and Engineering Aspects 539, 261-272, 2018
Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties
M Alahuhta, M Salin, MG Casteleijn, C Kemmer, I El-Sayed, K Augustyns, ...
Protein Engineering, Design & Selection 21 (4), 257-266, 2008
High-temperature cultivation and 5′ mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase …
K Szeker, O Niemitalo, MG Casteleijn, AH Juffer, P Neubauer
Journal of biotechnology 156 (4), 268-274, 2011
CD44 aptamer mediated cargo delivery to lysosomes of retinal pigment epithelial cells to prevent age-related macular degeneration
C Chandola, MG Casteleijn, UM Chandola, LN Gopalan, A Urtti, ...
Biochemistry and Biophysics Reports 18, 100642, 2019
Interaction of lecithin: cholesterol acyltransferase with lipid surfaces and apolipoprotein AI-derived peptides
MG Casteleijn, P Parkkila, T Viitala, A Koivuniemi
Journal of lipid research 59 (4), 670-683, 2018
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
M Salin, EG Kapetaniou, M Vaismaa, M Lajunen, MG Casteleijn, ...
Acta Crystallographica Section D: Biological Crystallography 66 (8), 934-944, 2010
Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric …
M Alahuhta, MG Casteleijn, P Neubauer, RK Wierenga
Acta Crystallographica Section D: Biological Crystallography 64 (2), 178-188, 2008
Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation
D Richardson, J Itkonen, J Nievas, A Urtti, MG Casteleijn
Scientific Reports 8 (1), 11967, 2018
Characterization, stability, and in vivo efficacy studies of recombinant human CNTF and its permeation into the neural retina in ex vivo organotypic retinal explant culture models
J Itkonen, A Annala, S Tavakoli, B Arango-Gonzalez, M Ueffing, ...
Pharmaceutics 12 (7), 611, 2020
Engineering cells and proteins – creating pharmaceuticals
MG Casteleijn, D Richardson
European Pharmaceutical Review 19 (4), 12-19, 2014
Towards new enzymes: protein engineering versus Bioinformatic studies
MG casteleijn
University of Oulu, 2009
Controlled high-cell density cultivation in shake flasks
J Panula-Perälä, M Casteleijn, A Vasala, P Neubauer
Journal of Biotechnology 2 (131), S182, 2007
Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy
J Itkonen, L Ghemtio, D Pellegrino, PJ Jokela, H Xhaard, MG Casteleijn
Pharmaceutics 14 (8), 1639, 2022
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