Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer’s disease C Rodríguez-Rodríguez, N Sanchez de Groot, A Rimola, ... Journal of the American Chemical Society 131 (4), 1436-1451, 2009 | 249 | 2009 |
An eighteen‐membered macrocyclic ligand for actinium‐225 targeted alpha therapy NA Thiele, V Brown, JM Kelly, A Amor‐Coarasa, U Jermilova, ... Angewandte Chemie International Edition 56 (46), 14712-14717, 2017 | 207 | 2017 |
The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases C Rodríguez-Rodríguez, M Telpoukhovskaia, C Orvig Coordination Chemistry Reviews 256 (19-20), 2308-2332, 2012 | 189 | 2012 |
Crystal structure of thioflavin-T and its binding to amyloid fibrils: insights at the molecular level C Rodríguez-Rodríguez, A Rimola, L Rodríguez-Santiago, P Ugliengo, ... Chemical Communications 46 (7), 1156-1158, 2010 | 100 | 2010 |
N-Aryl-substituted 3-(β-D-glucopyranosyloxy)-2-methyl-4 (1 H)-pyridinones as agents for Alzheimer's therapy LE Scott, M Telpoukhovskaia, C Rodríguez-Rodríguez, M Merkel, ... Chemical Science 2 (4), 642-648, 2011 | 86 | 2011 |
Multi-isotope SPECT imaging of the 225Ac decay chain: feasibility studies AKH Robertson, CF Ramogida, C Rodriguez-Rodriguez, S Blinder, ... Physics in Medicine & Biology 62 (11), 4406, 2017 | 56 | 2017 |
Synthesis and Evaluation of a Macrocyclic Actinium‐225 Chelator, Quality Control and In Vivo Evaluation of 225Ac‐crown‐αMSH Peptide H Yang, C Zhang, Z Yuan, C Rodriguez‐Rodriguez, A Robertson, ... Chemistry–A European Journal 26 (50), 11435-11440, 2020 | 51 | 2020 |
Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225 Ac CF Ramogida, AKH Robertson, U Jermilova, C Zhang, H Yang, P Kunz, ... EJNMMI Radiopharmacy and Chemistry 4, 1-20, 2019 | 50 | 2019 |
A new tetrapodal 3-hydroxy-4-pyridinone ligand for complexation of 89 zirconium for positron emission tomography (PET) imaging C Buchwalder, C Rodríguez-Rodríguez, P Schaffer, SK Karagiozov, ... Dalton Transactions 46 (29), 9654-9663, 2017 | 40 | 2017 |
Exploring the multifunctionality of thioflavin-and deferiprone-based molecules as acetylcholinesterase inhibitors for potential application in Alzheimer's disease MA Telpoukhovskaia, BO Patrick, C Rodríguez-Rodríguez, C Orvig Molecular BioSystems 9 (4), 792-805, 2013 | 37 | 2013 |
Monosized polymeric microspheres designed for passive lung targeting: biodistribution and pharmacokinetics after intravenous administration M Agnoletti, C Rodríguez-Rodríguez, SN Kłodzińska, TVF Esposito, ... ACS nano 14 (6), 6693-6706, 2020 | 36 | 2020 |
Ab initio design of chelating ligands relevant to Alzheimer’s disease: Influence of metalloaromaticity A Rimola, J Alí-Torres, C Rodríguez-Rodríguez, J Poater, E Matito, M Solà, ... The Journal of Physical Chemistry A 115 (45), 12659-12666, 2011 | 36 | 2011 |
H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry X Wang, MG Jaraquemada-Peláez, C Rodríguez-Rodríguez, Y Cao, ... Journal of the American Chemical Society 140 (45), 15487-15500, 2018 | 34 | 2018 |
Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles L Wu, C Rodríguez-Rodríguez, D Cun, M Yang, K Saatchi, UO Häfeli European Journal of Pharmaceutics and Biopharmaceutics 152, 108-115, 2020 | 31 | 2020 |
In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors MA Telpoukhovskaia, BO Patrick, C Rodríguez-Rodríguez, C Orvig Bioorganic & medicinal chemistry letters 26 (6), 1624-1628, 2016 | 31 | 2016 |
Dual-isotope SPECT/CT imaging of the tuberculosis subunit vaccine H56/CAF01: Induction of strong systemic and mucosal IgA and T-cell responses in mice upon subcutaneous prime … A Thakur, C Rodríguez-Rodríguez, K Saatchi, F Rose, T Esposito, ... Frontiers in immunology 9, 2825, 2018 | 26 | 2018 |
Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models C Rodríguez-Rodríguez, MA Telpoukhovskaia, J Alí-Torres, ... Metallomics 7 (1), 83-92, 2015 | 25 | 2015 |
3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeability MA Telpoukhovskaia, JF Cawthray, C Rodríguez-Rodríguez, LE Scott, ... Bioorganic & Medicinal Chemistry Letters 25 (17), 3654-3657, 2015 | 24 | 2015 |
3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents MA Telpoukhovskaia, C Rodríguez-Rodríguez, JF Cawthray, LE Scott, ... Metallomics 6 (2), 249-262, 2014 | 24 | 2014 |
Hybrid Metal–Phenol Nanoparticles with Polydopamine-like Coating for PET/SPECT/CT Imaging S Suarez-Garcia, TVF Esposito, J Neufeld-Peters, M Bergamo, H Yang, ... ACS applied materials & interfaces 13 (9), 10705-10718, 2021 | 23 | 2021 |