Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits U Styrkarsdottir, G Thorleifsson, P Sulem, DF Gudbjartsson, A Sigurdsson, ... Nature 497 (7450), 517-520, 2013 | 223 | 2013 |
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway C Praetorius, C Grill, SN Stacey, AM Metcalf, DU Gorkin, KC Robinson, ... Cell 155 (5), 1022-1033, 2013 | 151 | 2013 |
Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation S Heublein, S Kazi, MH Ögmundsdóttir, EV Attwood, S Kala, CAR Boyd, ... Oncogene 29 (28), 4068-4079, 2010 | 143 | 2010 |
Proton-Assisted Amino Acid Transporter PAT1 Complexes with Rag GTPases and Activates TORC1 on Late Endosomal and Lysosomal Membranes MH Ögmundsdóttir, S Heublein, S Kazi, B Reynolds, SM Visvalingam, ... PloS one 7 (5), e36616, 2012 | 117 | 2012 |
Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF V Pogenberg, MH Ögmundsdóttir, K Bergsteinsdóttir, A Schepsky, ... Genes & Development 26 (23), 2647-2658, 2012 | 96 | 2012 |
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth C Di Malta, D Siciliano, A Calcagni, J Monfregola, S Punzi, N Pastore, ... Science 356 (6343), 1188-1192, 2017 | 83 | 2017 |
Amino acid sensing and mTOR regulation; inside or out? DCI Goberdhan, MH Ögmundsdóttir, S Kazi, B Reynolds, S Visvalingam, ... Biochemical Society Transactions 37 (Pt 1), 248, 2009 | 59 | 2009 |
Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1 T Zhang, Q Zhou, MH Ogmundsdottir, K Möller, R Siddaway, L Larue, ... Journal of cell science 128 (15), 2938-2950, 2015 | 51 | 2015 |
MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function C Grill, K Bergsteinsdóttir, MH Ögmundsdóttir, V Pogenberg, A Schepsky, ... Human molecular genetics 22 (21), 4357-4367, 2013 | 48 | 2013 |
Duplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulence T Óskarsson, HS Hreggvidsdóttir, G Agnarsdóttir, S Matthíasdóttir, ... Journal of virology 81 (8), 4052-4057, 2007 | 47 | 2007 |
Proton-pump inhibitors among adults: a nationwide drug-utilization study ÓÖ Hálfdánarson, A Pottegård, ES Björnsson, SH Lund, ... Therapeutic advances in gastroenterology 11, 1756284818777943, 2018 | 41 | 2018 |
Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells M Bessadottir, M Egilsson, E Einarsdottir, IH Magnusdottir, ... PLoS One 7 (12), e51296, 2012 | 27 | 2012 |
MITF has a central role in regulating starvation-induced autophagy in melanoma K Möller, S Sigurbjornsdottir, AO Arnthorsson, V Pogenberg, R Dilshat, ... Scientific reports 9 (1), 1-12, 2019 | 23 | 2019 |
Subcellular localization and stability of MITF are modulated by the bHLH‐Zip domain V Fock, SR Gudmundsson, HO Gunnlaugsson, JA Stefansson, V Ionasz, ... Pigment cell & melanoma research 32 (1), 41-54, 2019 | 18 | 2019 |
Proton pump inhibitor use and risk of breast cancer, prostate cancer, and malignant melanoma: An Icelandic population‐based case‐control study ÓÖ Hálfdánarson, K Fall, MH Ogmundsdottir, SH Lund, E Steingrímsson, ... Pharmacoepidemiology and drug safety 28 (4), 471-478, 2019 | 7 | 2019 |
Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif V Pogenberg, J Ballesteros-Álvarez, R Schober, I Sigvaldadóttir, ... Nucleic acids research 48 (2), 934-948, 2020 | 3 | 2020 |
The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function A García-Llorca, SG Aspelund, MH Ogmundsdottir, E Steingrimsson, ... Scientific reports 9 (1), 1-12, 2019 | 2 | 2019 |
Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancer ÓÖ Hálfdánarson, A Pottegård, SH Lund, MH Ogmundsdottir, ... Basic & Clinical Pharmacology & Toxicology 126 (6), 484-491, 2020 | 1 | 2020 |
Genetic risk of cholangiocarcinoma is linked to the autophagy gene ATG7 SU Greer, MH Ogmundsdottir, J Chen, BT Lau, RGC Delacruz, ... BioRxiv, 836767, 2019 | 1 | 2019 |
A short isoform of ATG7 fails to lipidate LC3/GABARAP MH Ogmundsdottir, V Fock, L Sooman, V Pogenberg, R Dilshat, ... Scientific reports 8 (1), 1-8, 2018 | 1 | 2018 |