Tomoko KUWABARA, Ph.D.   E-MAIL ;
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Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
J Hsieh, K Nakashima, T Kuwabara, E Mejia, FH Gage
Proceedings of the National Academy of Sciences 101 (47), 16659-16664, 2004
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
T Kuwabara, J Hsieh, A Muotri, G Yeo, M Warashina, DC Lie, L Moore, ...
Nature neuroscience 12 (9), 1097-1105, 2009
A small modulatory dsRNA specifies the fate of adult neural stem cells
T Kuwabara, J Hsieh, K Nakashima, K Taira, FH Gage
Cell 116 (6), 779-793, 2004
Noncoding RNAs in the mammalian central nervous system
X Cao, G Yeo, AR Muotri, T Kuwabara, FH Gage
Annu. Rev. Neurosci. 29, 77-103, 2006
IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes
J Hsieh, JB Aimone, BK Kaspar, T Kuwabara, K Nakashima, FH Gage
Journal of Cell Biology 164 (1), 111-122, 2004
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation
BZ Barkho, H Song, JB Aimone, RD Smrt, T Kuwabara, K Nakashima, ...
Stem cells and development 15 (3), 407-421, 2006
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivo
T Kuwabara, M Warashina, T Tanabe, K Tani, S Asano, K Taira
Molecular cell 2 (5), 617-627, 1998
Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis
M Okamoto, K Inoue, H Iwamura, K Terashima, H Soya, M Asashima, ...
The FASEB Journal 25 (10), 3570-3582, 2011
RNA–protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA
M Warashina, T Kuwabara, Y Kato, M Sano, K Taira
Proceedings of the National Academy of Sciences 98 (10), 5572-5577, 2001
Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosome
M Warashina, T Kuwabara, Y Nakamatsu, K Taira
Chemistry & biology 6 (4), 237-250, 1999
Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells
Y Kato, T Kuwabara, M Warashina, H Toda, K Taira
Journal of Biological Chemistry 276 (18), 15378-15385, 2001
Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells
X Li, BZ Barkho, Y Luo, RD Smrt, NJ Santistevan, C Liu, T Kuwabara, ...
Journal of Biological Chemistry 283 (41), 27644-27652, 2008
Oncogene inactivation in a mouse model
T Tanabe, T Kuwabara, M Warashina, K Tani, K Taira, S Asano
Nature 406 (6795), 473-474, 2000
Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb
T Kuwabara, MN Kagalwala, Y Onuma, Y Ito, M Warashina, K Terashima, ...
EMBO molecular medicine 3 (12), 742-754, 2011
A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells
M Warashina, KH Min, T Kuwabara, A Huynh, FH Gage, PG Schultz, ...
Angewandte Chemie 118 (4), 605-607, 2006
tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: simultaneous cleavage at two sites in HIV-1 Tat mRNA in cultured cells
T Kuwabara, M Warashina, A Nakayama, J Ohkawa, K Taira
Proceedings of the National Academy of Sciences 96 (5), 1886-1891, 1999
Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA
T Kuwabara, M Warashina, T Tanabe, K Tani, S Asano, K Taira
Nucleic acids research 25 (15), 3074-3081, 1997
Formation of a catalytically active dimer by tRNA Val-driven short ribozymes
T Kuwabara, M Warashina, M Orita, S Koseki, J Ohkawa, K Taira
Nature biotechnology 16 (10), 961-965, 1998
Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running
S Fujimaki, R Hidaka, M Asashima, T Takemasa, T Kuwabara
Journal of biological chemistry 289 (11), 7399-7412, 2014
Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes
T Kuwabara, SV Amontov, M Warashina, J Ohkawa, K Taira
Nucleic acids research 24 (12), 2302-2310, 1996
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