Equivocal, explicit and emergent actions of PKC isoforms in cancer PJ Parker, SJ Brown, V Calleja, P Chakravarty, M Cobbaut, M Linch, ... Nature Reviews Cancer 21 (1), 51-63, 2021 | 45 | 2021 |
Dysfunctional mechanotransduction through the YAP/TAZ/Hippo pathway as a feature of chronic disease M Cobbaut, S Karagil, L Bruno, MDC Diaz de la Loza, FE Mackenzie, ... Cells 9 (1), 151, 2020 | 44 | 2020 |
Function and regulation of protein kinase D in oxidative stress: a tale of isoforms M Cobbaut, J Van Lint Oxidative Medicine and Cellular Longevity 2018, 2018 | 34 | 2018 |
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling D Bauters, M Cobbaut, L Geys, J Van Lint, B Hemmeryckx, HR Lijnen Molecular metabolism 6 (7), 715-724, 2017 | 30 | 2017 |
Protein kinase D2: a versatile player in cancer biology N Azoitei, M Cobbaut, A Becher, J Van Lint, T Seufferlein Oncogene 37 (10), 1263-1278, 2018 | 24 | 2018 |
Design, synthesis and biological evaluation of pyrazolo [3, 4-d] pyrimidine-based protein kinase D inhibitors P Gilles, RS Kashyap, MJ Freitas, S Ceusters, K Van Asch, A Janssens, ... European Journal of Medicinal Chemistry 205, 112638, 2020 | 17 | 2020 |
Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+ 1 loop M Cobbaut, R Derua, H Döppler, HJ Lou, S Vandoninck, P Storz, BE Turk, ... Scientific reports 7 (1), 887, 2017 | 17 | 2017 |
Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo [3, 4-d] pyrimidine analogues K Verschueren, M Cobbaut, J Demaerel, L Saadah, ARD Voet, J Van Lint, ... MedChemComm 8 (3), 640-646, 2017 | 14 | 2017 |
The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity A Elbediwy, Y Zhang, M Cobbaut, P Riou, RS Tan, SK Roberts, C Tynan, ... Journal of Cell Science 132 (8), jcs223743, 2019 | 13 | 2019 |
Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation M Cobbaut, R Derua, PJ Parker, E Waelkens, V Janssens, J Van Lint FEBS letters 592 (14), 2432-2443, 2018 | 9 | 2018 |
Control of atypical PKCι membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface M Cobbaut, NQ McDonald, PJ Parker Journal of Biological Chemistry 299 (7), 2023 | 3 | 2023 |
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells N Lockwood, S Martini, A Lopez-Pardo, K Deiss, HA Segeren, RK Semple, ... Cancer research 82 (9), 1762-1773, 2022 | 2 | 2022 |
Into the fold: advances in understanding aPKC membrane dynamics M Cobbaut, PJ Parker, NQ McDonald Biochemical Journal 480 (24), 2037-2044, 2023 | | 2023 |
A distinctive requirement for p53 in the genome protective Topoisomerase 2a-dependent G2 arrest in hTERT positive cancer cells N Lockwood, S Martini, A López-Pardo, K Deiss, HA Segeren, RK Semple, ... Cancer Research, 2022 | | 2022 |
First person–Mathias Cobbaut and Ahmed Elbediwy M Cobbaut, A Elbediwy Journal of Cell Science 132 (8), jcs231928, 2019 | | 2019 |
Design, Synthesis and Evaluation of Protein Kinase D Inhibitors P Gilles, K Verschueren, M Cobbaut, J Demaerel, J Van Lint, A Voet, ... Merck Organic Chemistry Symposium, Date: 2017/12/07-2017/12/08, Location …, 2017 | | 2017 |
Abstract B08: Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment M Cobbaut, R Derua, E Waelkens, P Störz, V Janssens, JV Lint Cancer Research 77 (22_Supplement), B08-B08, 2017 | | 2017 |
Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment M Cobbaut, R Derua, E Waelkens, P Storz, V Janssens, J Van Lint CANCER RESEARCH 77 (22), 2017 | | 2017 |
Nieuwe inzichten in de farmacologische inhibitie en isovormspecifieke regulatie van Proteine Kinase D2 M Cobbaut | | 2017 |
Identification of a zyxin family based network of novel Protein Kinase D interactors via BioID J Van Lint, R Derua, L Saadah, E Waelkens, V Janssens, M Cobbaut Novo Nordisk Copenhagen Bioscience Conference on Protein Signaling-from …, 2016 | | 2016 |