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Yusheng Jiang, Ph.D.
Yusheng Jiang, Ph.D.
FDA/CDER/OGD/ORS/DQMM
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2
IY Kuo, AL Brill, FO Lemos, JY Jiang, JL Falcone, EP Kimmerling, Y Cai, ...
Science signaling 12 (580), eaat7397, 2019
812019
Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation
JY Jiang, JL Falcone, S Curci, AM Hofer
Proceedings of the National Academy of Sciences 116 (24), 12066-12071, 2019
642019
Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1α (mGluR1α) that controls receptor activation
Y Jiang, Y Huang, HC Wong, Y Zhou, X Wang, J Yang, RA Hall, ...
Journal of biological chemistry 285 (43), 33463-33474, 2010
432010
Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium
C Zhang, Y Huang, Y Jiang, N Mulpuri, L Wei, D Hamelberg, EM Brown, ...
Journal of Biological Chemistry 289 (8), 5296-5309, 2014
402014
Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α
JY Jiang, M Nagaraju, RC Meyer, L Zhang, D Hamelberg, RA Hall, ...
Journal of Biological Chemistry 289 (3), 1649-1661, 2014
312014
Interrogating cyclic AMP signaling using optical approaches
JY Jiang, JL Falcone, S Curci, AM Hofer
Cell Calcium 64, 47-56, 2017
302017
A novel RUNX2 missense mutation predicted to disrupt DNA binding causes cleidocranial dysplasia in a large Chinese family with hyperplastic nails
S Tang, Q Xu, X Xu, J Du, X Yang, Y Jiang, X Wang, N Speck, T Huang
BMC Medical Genetics 8, 1-6, 2007
242007
Molecular Basis for Modulation of Metabotropic Glutamate Receptors and Their Drug Actions by Extracellular Ca2+
J Zou, JY Jiang, JJ Yang
International Journal of Molecular Sciences 18 (3), 672, 2017
122017
Epigenetic regulation of corneal epithelial differentiation by TET2
Y Sasamoto, S Wu, CAA Lee, JY Jiang, BR Ksander, MH Frank, NY Frank
International Journal of Molecular Sciences 24 (3), 2841, 2023
32023
Persistent cAMP Signaling via Vasopressin V2 Receptors Imaged in 3D Cultures Using Lightsheet Microscopy
J Jiang, I Kuo, J Abi‐Jaoude, F Lemos, Y Yang, S Curci, B Ehrlich, A Hofer
The FASEB Journal 29, LB632, 2015
22015
哺乳动物细胞 POLK, POLH, POLI 基因对甲基硝基亚硝基胍的应答反应及其启动子区转录因子结合部位的生物信息学分析
蒋余圣, 钱羽力, 余应年
中国病理生理杂志 22 (7), 1249-1255, 2006
22006
PDE8A Shapes The Profile of Cyclic AMP Signaling Events: Assessing The Importance of PKA‐dependent Feedback Regulation
JY Jiang, J Abi‐Jaoude, J Nichols, S Curci, A Hofer
The FASEB Journal 29, LB627, 2015
12015
Modulating drug effects against metabotropic glutamate receptor with extracellular calcium
JJ Yang, JY Jiang
US Patent 10,449,216, 2019
2019
Effects of Extracellular Calcium on the Modulation of Metabotropic Glutamate Receptor 1 Alpha (mGluR1α) by L-Quis,(S)-Mcpg, Cpccoet and Ro 67-4853
Y Jiang, R Meyer, HC Wong, X Wang, EM Brown, R Hall, J Conn, J Yang
Biophysical Journal 104 (2), 401a-402a, 2013
2013
Disease Related Mutations Adjacent to Predicted Multiple Ca2+ Binding Sites of Ca2+-Sensing Receptor Altering Intracellular Ca2+ Oscillations via Extracellular Calcium and …
C Zhang, F Hannan, Y Huang, Y Jiang, M Nagaraju, R Thakker, ...
Biophysical Journal 102 (3), 507a, 2012
2012
Modulating Drug Effects of Metabotropic Glutamate Receptor 1 Alpha (mGluR1α) by Extracellular Ca2+
Y Jiang, J Yang
Biophysical Journal 102 (3), 509a, 2012
2012
Designed Red Fluorescent Calcium Sensor with Ultrafast Kinetic Properties
Y Zhuo, S Tang, Y Jiang, F Reddish, H Wong, JJ Yang
Biophysical Journal 102 (3), 477a, 2012
2012
Calcium modulates mglur1 folding in ER in the trafficking process and regulates the drug activity upon the receptor expressing on the cell membrane
Y Jiang
Georgia State University, 2012
2012
Rational Design and Structural Analysis of Calcium Biosensors and their Application to the Study of SR/ER Calcium Dynamics
S Tang, Y Zhuo, Y Jiang, HC Wong, Z Wang, O Delbono, JJ Yang
Biophysical Journal 100 (3), 554a, 2011
2011
Differential Activation of Intracellular Calcium Oscillations by Multiple Calcium and L-Phenylalanine Binding Sites Located at the Extracellular Domain of Calcium-Sensing-Receptor
C Zhang, Y Huang, Y Jiang, H Wong, X Wang, A Castiblanco, L Wei, ...
Biophysical Journal 100 (3), 86a, 2011
2011
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