Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase JD McKinney, KH Zu Bentrup, EJ Muñoz-Elías, A Miczak, B Chen, ... Nature 406 (6797), 735-738, 2000 | 1746 | 2000 |
Immune control of tuberculosis by IFN-γ-inducible LRG-47 JD MacMicking, GA Taylor, JD McKinney Science 302 (5645), 654-659, 2003 | 895 | 2003 |
Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 883 | 2009 |
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence EJ Muñoz-Elías, JD McKinney Nature medicine 11 (6), 638-644, 2005 | 883 | 2005 |
M. tuberculosis persistence, latency, and drug tolerance JE Gomez, JD McKinney Tuberculosis 84 (1-2), 29-44, 2004 | 755 | 2004 |
Dynamic persistence of antibiotic-stressed mycobacteria Y Wakamoto, N Dhar, R Chait, K Schneider, F Signorino-Gelo, S Leibler, ... Science 339 (6115), 91-95, 2013 | 626 | 2013 |
Microbial phenotypic heterogeneity and antibiotic tolerance N Dhar, JD McKinney Current opinion in microbiology 10 (1), 30-38, 2007 | 434 | 2007 |
Role of KatG catalase‐peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst VH Ng, JS Cox, AO Sousa, JD MacMicking, JD McKinney Molecular microbiology 52 (5), 1291-1302, 2004 | 423 | 2004 |
Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence EJ Muñoz‐Elías, AM Upton, J Cherian, JD McKinney Molecular microbiology 60 (5), 1109-1122, 2006 | 414 | 2006 |
Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis V Sharma, S Sharma, KH Zu Bentrup, JD McKinney, DG Russell, ... Nature structural biology 7 (8), 663-668, 2000 | 348 | 2000 |
Carbon metabolism of intracellular bacteria EJ Muñoz‐Elías, JD McKinney Cellular microbiology 8 (1), 10-22, 2006 | 344 | 2006 |
Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients J Timm, FA Post, LG Bekker, GB Walther, HC Wainwright, R Manganelli, ... Proceedings of the National Academy of Sciences 100 (24), 14321-14326, 2003 | 330 | 2003 |
A problem of persistence: still more questions than answers? NQ Balaban, K Gerdes, K Lewis, JD McKinney Nature Reviews Microbiology 11 (8), 587-591, 2013 | 325 | 2013 |
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms G Manina, N Dhar, JD McKinney Cell host & microbe 17 (1), 32-46, 2015 | 324 | 2015 |
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations JE Griffin, AK Pandey, SA Gilmore, V Mizrahi, JD Mckinney, CR Bertozzi, ... Chemistry & biology 19 (2), 218-227, 2012 | 316 | 2012 |
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism A Koul, L Vranckx, N Dhar, HWH Göhlmann, E Özdemir, JM Neefs, ... Nature communications 5 (1), 3369, 2014 | 301 | 2014 |
Replication Dynamics of Mycobacterium tuberculosis in Chronically Infected Mice EJ Muñoz-Elías, J Timm, T Botha, WT Chan, JE Gomez, JD McKinney Infection and immunity 73 (1), 546-551, 2005 | 291 | 2005 |
Functional Characterization of a Vitamin B12-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during … S Savvi, DF Warner, BD Kana, JD McKinney, V Mizrahi, SS Dawes Journal of bacteriology 190 (11), 3886-3895, 2008 | 288 | 2008 |
Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis TA Gould, H Van De Langemheen, EJ Muñoz‐Elías, JD McKinney, ... Molecular microbiology 61 (4), 940-947, 2006 | 223 | 2006 |
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012 | 220 | 2012 |