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David Rusling
David Rusling
Senior Lecturer in Pharmacology
Verified email at port.ac.uk
Title
Cited by
Cited by
Year
Footprinting: a method for determining the sequence selectivity, affinity and kinetics of DNA-binding ligands
AJ Hampshire, DA Rusling, VJ Broughton-Head, KR Fox
Methods 42 (2), 128-140, 2007
1852007
Four base recognition by triplex-forming oligonucleotides at physiological pH
DA Rusling, VEC Powers, RT Ranasinghe, Y Wang, SD Osborne, ...
Nucleic acids research 33 (9), 3025-3032, 2005
1492005
Triplex-forming oligonucleotides: a third strand for DNA nanotechnology
AR Chandrasekaran, DA Rusling
Nucleic acids research 46 (3), 1021-1037, 2018
842018
Functionalizing designer DNA crystals with a triple‐helical veneer
DA Rusling, AR Chandrasekaran, YP Ohayon, T Brown, KR Fox, R Sha, ...
Angewandte Chemie 126 (15), 4060-4063, 2014
712014
Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside
Y Wang, DA Rusling, VEC Powers, O Lack, SD Osborne, KR Fox, T Brown
Biochemistry 44 (15), 5884-5892, 2005
552005
Selectivity and affinity of triplex-forming oligonucleotides containing 2′-aminoethoxy-5-(3-aminoprop-1-ynyl) uridine for recognizing AT base pairs in duplex DNA
SD Osborne, VEC Powers, DA Rusling, O Lack, KR Fox, T Brown
Nucleic acids research 32 (15), 4439-4447, 2004
542004
Sequence-specific DNA binding agents
D Patel, N Dias, D Graves, JB Chaires, F Gago, L Hurley, D Sun, ...
Royal Society of Chemistry, 2007
442007
DNA looping by FokI: the impact of twisting and bending rigidity on protein-induced looping dynamics
N Laurens, DA Rusling, C Pernstich, I Brouwer, SE Halford, GJL Wuite
Nucleic acids research 40 (11), 4988-4997, 2012
432012
Stabilisation of self-assembled DNA crystals by triplex-directed photo-cross-linking
HO Abdallah, YP Ohayon, AR Chandrasekaran, R Sha, KR Fox, T Brown, ...
Chemical communications 52 (51), 8014-8017, 2016
392016
Recognition of CG inversions in DNA triple helices by methylated 3 H-pyrrolo [2, 3-d] pyrimidin-2 (7 H)-one nucleoside analogues
RT Ranasinghe, DA Rusling, VEC Powers, KR Fox, T Brown
Chemical communications, 2555-2557, 2005
392005
Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange
DA Rusling, IS Nandhakumar, T Brown, KR Fox
ACS nano 6 (4), 3604-3613, 2012
372012
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine
DA Rusling, G Peng, N Srinivasan, KR Fox, T Brown
Nucleic acids research 37 (4), 1288-1296, 2009
282009
Triplex-directed covalent cross-linking of a DNA nanostructure
DA Rusling, IS Nandhakumar, T Brown, KR Fox
Chemical communications 48 (77), 9592-9594, 2012
262012
Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex-forming oligonucleotides at physiological pH
DA Rusling, L Le Strat, VEC Powers, VJ Broughton-Head, J Booth, O Lack, ...
FEBS letters 579 (29), 6616-6620, 2005
262005
Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2′-O-(2-aminoethyl)-5-(3-amino-1-propynyl) uridine
DA Rusling, VJ Broughton-Head, A Tuck, H Khairallah, SD Osborne, ...
Organic & Biomolecular Chemistry 6 (1), 122-129, 2008
252008
The reaction mechanism of FokI excludes the possibility of targeting zinc finger nucleases to unique DNA sites
SE Halford, LE Catto, C Pernstich, DA Rusling, KL Sanders
Biochemical Society Transactions 39 (2), 584-588, 2011
232011
The stability of triplex DNA is affected by the stability of the underlying duplex
DA Rusling, PA Rachwal, T Brown, KR Fox
Biophysical chemistry 145 (2-3), 105-110, 2009
202009
Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides
KR Fox, DA Rusling, VJ Broughton-Head, T Brown
Current Chemical Biology 2 (1), 1-10, 2008
182008
DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations
DA Rusling, N Laurens, C Pernstich, GJL Wuite, SE Halford
Nucleic acids research 40 (11), 4977-4987, 2012
172012
DNA triple-helix formation at target sites containing duplex mismatches
DA Rusling, T Brown, KR Fox
Biophysical chemistry 123 (2-3), 134-140, 2006
162006
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