Multiplex digital spatial profiling of proteins and RNA in fixed tissue CR Merritt, GT Ong, SE Church, K Barker, P Danaher, G Geiss, M Hoang, ... Nature biotechnology 38 (5), 586-599, 2020 | 615 | 2020 |
Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 305 | 2021 |
Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing ML Hoang, CH Chen, VS Sidorenko, J He, KG Dickman, BH Yun, ... Science translational medicine 5 (197), 197ra102-197ra102, 2013 | 286 | 2013 |
Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing ML Hoang, I Kinde, C Tomasetti, KW McMahon, TA Rosenquist, ... Proceedings of the National Academy of Sciences 113 (35), 9846-9851, 2016 | 205 | 2016 |
High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging S He, R Bhatt, C Brown, EA Brown, DL Buhr, K Chantranuvatana, ... Nature Biotechnology 40 (12), 1794-1806, 2022 | 181 | 2022 |
Inter-and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling L Brady, M Kriner, I Coleman, C Morrissey, M Roudier, LD True, R Gulati, ... Nature communications 12 (1), 1426, 2021 | 175 | 2021 |
Loss of heterozygosity drives adaptation in hybrid yeast CSS Heil, CG DeSevo, DA Pai, CM Tucker, ML Hoang, MJ Dunham Molecular biology and evolution 34 (7), 1596, 2017 | 90 | 2017 |
Loss of heterozygosity drives adaptation in hybrid yeast CS Smukowski Heil, CG DeSevo, DA Pai, CM Tucker, ML Hoang, ... Molecular biology and evolution 34 (7), 1596-1612, 2017 | 90 | 2017 |
Aristolochic acid in the etiology of renal cell carcinoma ML Hoang, CH Chen, PC Chen, NJ Roberts, KG Dickman, BH Yun, ... Cancer Epidemiology, Biomarkers & Prevention 25 (12), 1600-1608, 2016 | 81 | 2016 |
Ribosomal DNA Replication Fork Barrier and HOT1 Recombination Hot Spot: Shared Sequences but Independent Activities TR Ward, ML Hoang, R Prusty, CK Lau, RL Keil, WL Fangman, BJ Brewer Molecular and cellular biology 20 (13), 4948-4957, 2000 | 80 | 2000 |
Structural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae ML Hoang, RP Leon, L Pessoa-Brandao, S Hunt, MK Raghuraman, ... Molecular and cellular biology 27 (21), 7594-7602, 2007 | 76 | 2007 |
Competitive repair by naturally dispersed repetitive DNA during non-allelic homologous recombination ML Hoang, FJ Tan, DC Lai, SE Celniker, RA Hoskins, MJ Dunham, ... PLoS genetics 6 (12), e1001228, 2010 | 71 | 2010 |
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler H Bergholtz, JM Carter, A Cesano, MCU Cheang, SE Church, P Divakar, ... Cancers 13 (17), 4456, 2021 | 61 | 2021 |
Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response KL McNamara, JL Caswell-Jin, R Joshi, Z Ma, E Kotler, GR Bean, ... Nature cancer 2 (4), 400-413, 2021 | 60 | 2021 |
High-plex multiomic analysis in FFPE tissue at single-cellular and subcellular resolution by spatial molecular imaging S He, R Bhatt, B Birditt, C Brown, E Brown, K Chantranuvatana, ... bioRxiv, 2021.11. 03.467020, 2021 | 57 | 2021 |
Chemical compositions and methods of using same DL Dunaway, EA Manrao, JM Beechem, R Khafizov, S Korukonda, ... US Patent 10,415,080, 2019 | 51 | 2019 |
Mutational processes in hepatocellular carcinoma: the story of aristolochic acid JC Nault, E Letouzé Seminars in liver disease 39 (03), 334-340, 2019 | 30 | 2019 |
Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling SM Zimmerman, R Fropf, BR Kulasekara, M Griswold, O Appelbe, ... Genome research 32 (10), 1892-1905, 2022 | 29 | 2022 |
Differential paralog divergence modulates genome evolution across yeast species MR Sanchez, AW Miller, I Liachko, AB Sunshine, B Lynch, M Huang, ... PLoS Genetics 13 (2), e1006585, 2017 | 27 | 2017 |
Persistent mechanical linkage between sister chromatids throughout anaphase BD Harrison, ML Hoang, K Bloom Chromosoma 118, 633-645, 2009 | 25 | 2009 |