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Yen Sia Low
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Text mining for adverse drug events: the promise, challenges, and state of the art
R Harpaz, A Callahan, S Tamang, Y Low, D Odgers, S Finlayson, K Jung, ...
Drug safety 37, 777-790, 2014
2562014
Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches
Y Low, T Uehara, Y Minowa, H Yamada, Y Ohno, T Urushidani, A Sedykh, ...
Chemical research in toxicology 24 (8), 1251-1262, 2011
2252011
Integrative chemical–biological read-across approach for chemical hazard classification
Y Low, A Sedykh, D Fourches, A Golbraikh, M Whelan, I Rusyn, ...
Chemical research in toxicology 26 (8), 1199-1208, 2013
1372013
Alarms about structural alerts
VM Alves, EN Muratov, SJ Capuzzi, R Politi, Y Low, RC Braga, ...
Green Chemistry 18 (16), 4348-4360, 2016
1292016
Predictive modeling of chemical hazard by integrating numerical descriptors of chemical structures and short-term toxicity assay data
I Rusyn, A Sedykh, Y Low, KZ Guyton, A Tropsha
Toxicological Sciences 127 (1), 1-9, 2012
812012
Repurposing cAMP-modulating medications to promote β-cell replication
Z Zhao, YS Low, NA Armstrong, JH Ryu, SA Sun, AC Arvanites, ...
Molecular endocrinology 28 (10), 1682-1697, 2014
342014
Comparing high-dimensional confounder control methods for rapid cohort studies from electronic health records
YS Low, B Gallego, NH Shah
Journal of comparative effectiveness research 5 (2), 179-192, 2016
322016
Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays
Y Sia Low, A Yeugenyevich Sedykh, I Rusyn, A Tropsha
Current topics in medicinal chemistry 14 (11), 1356-1364, 2014
192014
Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome
YS Low, O Caster, T Bergvall, D Fourches, X Zang, GN Norén, I Rusyn, ...
Journal of the American Medical Informatics Association 23 (5), 968-978, 2016
182016
Synergistic drug combinations from electronic health records and gene expression
YS Low, AC Daugherty, EA Schroeder, W Chen, T Seto, S Weber, M Lim, ...
Journal of the American Medical Informatics Association 24 (3), 565-576, 2017
172017
A widely distributed gene cluster compensates for uricase loss in hominids
Y Liu, JB Jarman, YS Low, HE Augustijn, S Huang, H Chen, ME DeFeo, ...
Cell 186 (16), 3400-3413. e20, 2023
152023
Lymphopenia after adjuvant radiotherapy (RT) to predict poor survival in triple-negative breast cancer (TNBC).
A Afghahi, M Mathur, T Seto, M Desai, P Kenkare, KC Horst, AK Das, ...
Journal of Clinical Oncology 33 (15_suppl), 1069-1069, 2015
122015
Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure–Activity Relationships
YS Low, VM Alves, D Fourches, A Sedykh, CH Andrade, EN Muratov, ...
Journal of chemical information and modeling 58 (11), 2203-2213, 2018
82018
Real world evidence comparison of first-line (1L) immune-oncology (IO)/tyrosine kinase inhibitor (TKI) vs. IO/IO combination therapy in renal cell carcinoma (RCC).
P Bolan, G Hui, Y Low, S Gombar, AC Fan, DA Parikh, S Shah, S Srinivas, ...
Journal of Clinical Oncology 42 (4_suppl), 402-402, 2024
2024
Testing an informatics consulting service for systematic bias using negative control reference sets
M Jackson, S Gombar, R Manickam, R Brown, R Tekumalla, P Ballentine, ...
2024
Quantifying Fit-for-Purpose in Real World Data: Data Grading and FitQ Scores
ML Jackson, R Manickam, D Derieg, S Gombar, YS Low
medRxiv, 2024.02. 02.24302239, 2024
2024
System and Method for Rapid Informatics-Based Prognosis and Treatment Development
S Gombar, N Shah, YS Low, V Polony, U Reddy
US Patent App. 18/056,028, 2023
2023
Failure To Achieve Optimal Blood Pressure Control Among Stroke Patients In The Outpatient Setting
A Sreekrishnan, MG Lansberg, Y Low, R Manickam, L Kraler
Hypertension 79 (Suppl_1), A036-A036, 2022
2022
Pattern mining of drug prescriptions suggests complications from chronic opioid use
Y Low, T Podchiyska, N Shah, A Lembke
Pharmacoepidemiology and Drug Safety 24, 226, 2015
2015
Alerts about toxicity alerts
A Tropsha, D Fourches, R Politi, Y Low, E Muratov
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
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Articles 1–20