Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification S McGarrity, Ó Anuforo, H Halldórsson, A Bergmann, S Halldórsson, ... Scientific reports 8 (1), 6811, 2018 | 37 | 2018 |
Metabolic systems analysis of shock-induced endotheliopathy (SHINE) in trauma: a new research paradigm HH Henriksen, S McGarrity, RS SigurÐardóttir, T Nemkov, A D’Alessandro, ... Annals of Surgery 272 (6), 1140-1148, 2020 | 24 | 2020 |
Current status and future prospects of genome-scale metabolic modeling to optimize the use of mesenchymal stem cells in regenerative medicine Þ Sigmarsdóttir, S McGarrity, Ó Rolfsson, JT Yurkovich, ÓE Sigurjónsson Frontiers in Bioengineering and Biotechnology 8, 239, 2020 | 19 | 2020 |
Liquid chromatography–mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients SA Coulthard, P Berry, S McGarrity, A Ansari, CPF Redfern Journal of Chromatography B 1028, 175-180, 2016 | 15 | 2016 |
Azathioprine with allopurinol: lower deoxythioguanosine in DNA and transcriptome changes indicate mechanistic differences to azathioprine alone SA Coulthard, P Berry, S McGarrity, S McLaughlin, A Ansari, CPF Redfern Inflammatory Bowel Diseases 23 (6), 946-955, 2017 | 12 | 2017 |
Understanding the causes and implications of endothelial metabolic variation in cardiovascular disease through genome-scale metabolic modeling S McGarrity, H Halldórsson, S Palsson, PI Johansson, Ó Rolfsson Frontiers in Cardiovascular Medicine 3, 10, 2016 | 11 | 2016 |
Three faces of mercaptopurine cytotoxicity in vitro: methylation, nucleotide homeostasis, and deoxythioguanosine in DNA SA Coulthard, S McGarrity, K Sahota, P Berry, CPF Redfern Drug Metabolism and Disposition 46 (8), 1191-1199, 2018 | 10 | 2018 |
Metabolic and transcriptional changes across osteogenic differentiation of mesenchymal stromal cells TB Sigmarsdottir, S McGarrity, ALG de Lomana, A Kotronoulas, ... Bioengineering 8 (12), 208, 2021 | 8 | 2021 |
Metabolic response in endothelial cells to catecholamine stimulation associated with increased vascular permeability A López García de Lomana, AI Vilhjálmsson, S McGarrity, R Sigurðardóttir, ... International journal of molecular sciences 23 (6), 3162, 2022 | 7 | 2022 |
Analyzing metabolic states of adipogenic and osteogenic differentiation in human mesenchymal stem cells via genome scale metabolic model reconstruction TB Sigmarsdottir, S McGarrity, JT Yurkovich, Ó Rolfsson, ÓE Sigurjónsson Frontiers in Cell and Developmental Biology 9, 642681, 2021 | 5 | 2021 |
MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia CA Copeland, BA Olenchock, D Ziehr, S McGarrity, K Leahy, JD Young, ... Elife 12, e82597, 2023 | 3 | 2023 |
Comparative metabolic network flux analysis to identify differences in cellular metabolism S McGarrity, ST Karvelsson, ÓE Sigurjónsson, Ó Rolfsson Metabolic Flux Analysis in Eukaryotic Cells: Methods and Protocols, 223-269, 2020 | 3 | 2020 |
PWE-028 A Novel Assay for The Direct Detection of Deoxythioguanosine (DTG) in DNA from Patients On Azathioprine Using Liquid Chromatography and Tandem Mass Spectrometry (LC-MS/MS) S Coulthard, P Berry, S McGarrity, C Redfern Gut 65, A151, 2016 | 1 | 2016 |
LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage PI Johansson, HH Henriksen, ST Karvelsson, Ó Rolfsson, ... European Journal of Medical Research 29 (1), 71, 2024 | | 2024 |
How 3, 4, 5-Trihydroxycinnamic Acid Targets Vascular Leakage: Potential Targeted Sepsis Treatment S McGarrity Journal of Vascular Research 57 (5), 311-312, 2020 | | 2020 |
PTH-085 Deoxythioguanosine (DTG) in DNA as a Pharmacological Endpoint of Thiopurine Treatment in Inflammatory Bowel Disease Patients S Coulthard, P Berry, S McGarrity, T Kobayashi, T Toyonaga, A Ansari, ... Gut 65 (Suppl 1), A261-A261, 2016 | | 2016 |
A computational model of thiopurine metabolism S McGarrity Newcastle University, 2015 | | 2015 |
PWE-099 Direct Detection Of Thiopurine Metabolites In Erythrocytes And Leukocytes Using A Novel Lcms/ms Method To Interrogate Drug Response And in Vivo Metabolism SA Coulthard, P Berry, S McGarrity, CP Redfern, A Ansari Gut 63 (Suppl 1), A167-A168, 2014 | | 2014 |