Sarah McGarrity
Sarah McGarrity
University of Iceland/Brigham and Women's Hospital Harvard Medical School
Verified email at - Homepage
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Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification
S McGarrity, Ó Anuforo, H Halldórsson, A Bergmann, S Halldórsson, ...
Scientific reports 8 (1), 1-14, 2018
Current status and future prospects of genome-scale metabolic modeling to optimize the use of mesenchymal stem cells in regenerative medicine
Ţ Sigmarsdóttir, S McGarrity, Ó Rolfsson, JT Yurkovich, ÓE Sigurjónsson
Frontiers in Bioengineering and Biotechnology 8, 239, 2020
Metabolic systems analysis of shock-induced endotheliopathy (SHINE) in trauma: a new research paradigm
HH Henriksen, S McGarrity, RS SigurĐardóttir, T Nemkov, A D’Alessandro, ...
Annals of Surgery 272 (6), 1140-1148, 2020
Liquid chromatography–mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients
SA Coulthard, P Berry, S McGarrity, A Ansari, CPF Redfern
Journal of Chromatography B 1028, 175-180, 2016
Azathioprine with allopurinol: lower deoxythioguanosine in DNA and transcriptome changes indicate mechanistic differences to azathioprine alone
SA Coulthard, P Berry, S McGarrity, S McLaughlin, A Ansari, CPF Redfern
Inflammatory bowel diseases 23 (6), 946-955, 2017
Understanding the causes and implications of endothelial metabolic variation in cardiovascular disease through genome-scale metabolic modeling
S McGarrity, H Halldórsson, S Palsson, PI Johansson, Ó Rolfsson
Frontiers in Cardiovascular Medicine 3, 10, 2016
Three faces of mercaptopurine cytotoxicity in vitro: methylation, nucleotide homeostasis, and deoxythioguanosine in DNA
SA Coulthard, S McGarrity, K Sahota, P Berry, CPF Redfern
Drug Metabolism and Disposition 46 (8), 1191-1199, 2018
Analyzing metabolic states of adipogenic and osteogenic differentiation in human mesenchymal stem cells via genome scale metabolic model reconstruction
TB Sigmarsdottir, S McGarrity, JT Yurkovich, Ó Rolfsson, ÓE Sigurjónsson
Frontiers in cell and developmental biology 9, 1311, 2021
Metabolic response in endothelial cells to catecholamine stimulation associated with increased vascular permeability
A López García de Lomana, AI Vilhjálmsson, S McGarrity, R Sigurđardóttir, ...
International journal of molecular sciences 23 (6), 3162, 2022
Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells
TB Sigmarsdottir, S McGarrity, ALG de Lomana, A Kotronoulas, ...
Bioengineering 8 (12), 208, 2021
Comparative metabolic network flux analysis to identify differences in cellular metabolism
S McGarrity, ST Karvelsson, ÓE Sigurjónsson, Ó Rolfsson
Metabolic Flux Analysis in Eukaryotic Cells, 223-269, 2020
MYC uncouples HIF target gene expression from glycolytic flux in hypoxic proliferating primary cells
CA Copeland, BA Olenchock, DR Ziehr, S McGarrity, K Leahy, JD Young, ...
bioRxiv, 2020.09. 21.306464, 2021
Metabolic and Transcriptional Changes across Osteogenic Differentiation of Mesenchymal Stromal Cells
A Kotronoulas, TB Sigmarsdottir, ALG de Lomana, JT Yurkovich, ...
Bioengineering, 2021
How 3, 4, 5-Trihydroxycinnamic Acid Targets Vascular Leakage: Potential Targeted Sepsis Treatment.
S McGarrity
Journal of Vascular Research 57 (5), 311-313, 2020
PWE-028 A Novel Assay for The Direct Detection of Deoxythioguanosine (DTG) in DNA from Patients On Azathioprine Using Liquid Chromatography and Tandem Mass Spectrometry (LC-MS/MS)
S Coulthard, P Berry, S McGarrity, C Redfern
Gut 65, A151, 2016
PTH-085 Deoxythioguanosine (DTG) in DNA as a Pharmacological Endpoint of Thiopurine Treatment in Inflammatory Bowel Disease Patients
S Coulthard, P Berry, S McGarrity, T Kobayashi, T Toyonaga, A Ansari, ...
Gut 65 (Suppl 1), A261-A261, 2016
A computational model of thiopurine metabolism
S McGarrity
Newcastle University, 2015
PWE-099 Direct Detection Of Thiopurine Metabolites In Erythrocytes And Leukocytes Using A Novel Lcms/ms Method To Interrogate Drug Response And in Vivo Metabolism
SA Coulthard, P Berry, S McGarrity, CP Redfern, A Ansari
Gut 63 (Suppl 1), A167-A168, 2014
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