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Douglas Fuerst
Douglas Fuerst
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Title
Cited by
Cited by
Year
Thiourea-catalyzed enantioselective cyanosilylation of ketones
DE Fuerst, EN Jacobsen
Journal of the American Chemical Society 127 (25), 8964-8965, 2005
4112005
Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase
M Schober, C MacDermaid, AA Ollis, S Chang, D Khan, J Hosford, ...
Nature Catalysis 2 (10), 909-915, 2019
1592019
Synthesis of C (3) benzofuran-derived bisaryl quaternary centers: Approaches to diazonamide A
DE Fuerst, BM Stoltz, JL Wood
Organic letters 2 (22), 3521-3523, 2000
1212000
A designed photoenzyme for enantioselective [2+ 2] cycloadditions
JS Trimble, R Crawshaw, FJ Hardy, CW Levy, MJB Brown, DE Fuerst, ...
Nature 611 (7937), 709-714, 2022
672022
Enzymatic amidation for industrial applications
BM Dorr, DE Fuerst
Current Opinion in Chemical Biology 43, 127-133, 2018
502018
Rhodium-catalyzed synthesis of a C (3) disubstituted oxindole: an approach to diazonamide A
T Sawada, DE Fuerst, JL Wood
Tetrahedron letters 44 (26), 4919-4921, 2003
492003
Biocatalysis in medicinal chemistry: Challenges to access and drivers for adoption
NC Goodwin, JP Morrison, DE Fuerst, T Hadi
ACS Medicinal Chemistry Letters 10 (10), 1363-1366, 2019
262019
Identification and implementation of biocatalytic transformations in route discovery: synthesis of chiral 1, 3-substituted cyclohexanone building blocks
T Hadi, A Dı́az-Rodrı́guez, D Khan, JP Morrison, JM Kaplan, KT Gallagher, ...
Organic Process Research & Development 22 (7), 871-879, 2018
212018
Development of an Enzymatic Process for the Production of (R)-2-Butyl-2-ethyloxirane
GD Roiban, PW Sutton, R Splain, C Morgan, A Fosberry, K Honicker, ...
Organic Process Research & Development 21 (9), 1302-1310, 2017
142017
Rolling circle amplification of synthetic DNA accelerates biocatalytic determination of enzyme activity relative to conventional methods
T Hadi, N Nozzi, JO Melby, W Gao, DE Fuerst, E Kvam
Scientific Reports 10 (1), 10279, 2020
112020
Carboxyesterase polypeptides for amide coupling
R Voladri, D Entwistle, CM Micklitsch, V Mitchell, N Dellas, X Zhang, ...
US Patent 11,015,180, 2021
32021
Directed evolution of enzymes driving innovation in API manufacturing at GSK
J Latham, AA Ollis, C MacDermaid, K Honicker, D Fuerst, GD Roiban
Applied Biocatalysis: The Chemist's Enzyme Toolbox, 1-25, 2020
32020
Synthesis of bis‐3‐alkyl‐5‐arylhydantoins and bis‐3‐alkyl‐5‐arylthiohydantoins separated by two and four carbon atoms
OL Salerni, WK Van Tyle, DJ Mustra, KS Emerich, DE Fuerst, ...
Journal of heterocyclic chemistry 36 (5), 1179-1182, 1999
21999
Carboxyesterase biocatalysts
KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ...
US Patent 11,535,833, 2022
12022
Modification of saponins
M Brown, E Chapman, A Collis, D Fuerst, J Hosford, C Macdermaid, ...
US Patent App. 18/039,514, 2024
2024
Carboxyesterase biocatalysts
KK Brown, BM Dorr, DE Fuerst, KJ Honicker, LS Jordan, JP Morrison, ...
US Patent App. 18/046,295, 2023
2023
A Designed Photoenzyme Promotes Enantioselective [2+ 2]-Cycloadditions via Triplet Energy Transfer
A Green, J Trimble, R Crawshaw, F Hardy, C Levy, M Brown, D Fuerst, ...
2022
Biocatalytic Resolutions
P Clayman, GD Roiban, D Fuerst
Elsevier, 2022
2022
Carboxyesterase polypeptides for amide coupling
R Voladri, D Entwistle, CM Micklitsch, V Mitchell, N Dellas, X Zhang, ...
US Patent App. 17/236,928, 2021
2021
7.5 Preparation of Methyl (S)-3-Oxocyclohexanecarboxylate Using an Enoate Reductase
A Diaz-Rodriguez, T Hadi, R Snajdrova, D Fuerst, GD Roiban
Applied Biocatalysis, 277, 2021
2021
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