| C9orf72 is required for proper macrophage and microglial function in mice JG O’rourke, L Bogdanik, A Yáñez, D Lall, AJ Wolf, A Muhammad, R Ho, ... Science 351 (6279), 1324-1329, 2016 | 582 | 2016 |
| The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord B Deneen, R Ho, A Lukaszewicz, CJ Hochstim, RM Gronostajski, ... Neuron 52 (6), 953-968, 2006 | 523 | 2006 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 390 | 2018 |
| C9orf72 BAC transgenic mice display typical pathologic features of ALS/FTD JG O’Rourke, L Bogdanik, A Muhammad, TF Gendron, KJ Kim, A Austin, ... Neuron 88 (5), 892-901, 2015 | 324 | 2015 |
| Modeling ALS with motor neurons derived from human induced pluripotent stem cells S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ... Nature neuroscience 19 (4), 542-553, 2016 | 299 | 2016 |
| Modeling psychomotor retardation using iPSCs from MCT8-deficient patients indicates a prominent role for the blood-brain barrier GD Vatine, A Al-Ahmad, BK Barriga, S Svendsen, A Salim, L Garcia, ... Cell stem cell 20 (6), 831-843. e5, 2017 | 204 | 2017 |
| C9orf72 in myeloid cells suppresses STING-induced inflammation ME McCauley, JG O’Rourke, A Yáñez, JL Markman, R Ho, X Wang, ... Nature 585 (7823), 96-101, 2020 | 191 | 2020 |
| Human iPSC-derived endothelial cells and microengineered organ-chip enhance neuronal development S Sances, R Ho, G Vatine, D West, A Laperle, A Meyer, M Godoy, PS Kay, ... Stem cell reports 10 (4), 1222-1236, 2018 | 146 | 2018 |
| X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency V Pasque, J Tchieu, R Karnik, M Uyeda, AS Dimashkie, D Case, B Papp, ... Cell 159 (7), 1681-1697, 2014 | 117 | 2014 |
| iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates AH Laperle, S Sances, N Yucer, VJ Dardov, VJ Garcia, R Ho, AN Fulton, ... Nature medicine 26 (2), 289-299, 2020 | 111 | 2020 |
| Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins R Ho, B Papp, JA Hoffman, BJ Merrill, K Plath Cell reports 3 (6), 2113-2126, 2013 | 110 | 2013 |
| ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks R Ho, S Sances, G Gowing, MW Amoroso, JG O'Rourke, A Sahabian, ... Nature neuroscience 19 (9), 1256-1267, 2016 | 107 | 2016 |
| Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model Y Zhou, S Carmona, A Muhammad, S Bell, J Landeros, M Vazquez, R Ho, ... The Journal of clinical investigation 129 (4), 1756-1771, 2019 | 90 | 2019 |
| Mechanistic insights into reprogramming to induced pluripotency R Ho, C Chronis, K Plath Journal of cellular physiology 226 (4), 868-878, 2011 | 70 | 2011 |
| Cross-comparison of human iPSC motor neuron models of familial and sporadic ALS reveals early and convergent transcriptomic disease signatures R Ho, MJ Workman, P Mathkar, K Wu, KJ Kim, JG O’Rourke, M Kellogg, ... Cell systems 12 (2), 159-175. e9, 2021 | 38 | 2021 |
| Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects MJ Workman, RG Lim, J Wu, A Frank, L Ornelas, L Panther, E Galvez, ... Neuron 111 (8), 1191-1204. e5, 2023 | 21 | 2023 |
| CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity W Guo, H Wang, A Kumar Tharkeshwar, J Couthouis, E Braems, ... Alzheimer's & Dementia 19 (4), 1245-1259, 2023 | 12 | 2023 |
| Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis A Catanese, S Rajkumar, D Sommer, P Masrori, N Hersmus, ... Brain 146 (9), 3770-3782, 2023 | 11 | 2023 |
| Single-cell atlas unveils cellular heterogeneity and novel markers in human neonatal and adult intervertebral discs W Jiang, JD Glaeser, K Salehi, G Kaneda, P Mathkar, A Wagner, R Ho, ... Iscience 25 (7), 2022 | 11 | 2022 |
| HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS E Braems, V Bercier, E Van Schoor, K Heeren, J Beckers, L Fumagalli, ... Acta Neuropathologica 144 (3), 465-488, 2022 | 9 | 2022 |
