Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology PJ Harrison, AJ Law Biological psychiatry 60 (2), 132-140, 2006 | 580 | 2006 |
Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease AJ Law, BK Lipska, CS Weickert, TM Hyde, RE Straub, R Hashimoto, ... Proceedings of the National Academy of Sciences 103 (17), 6747-6752, 2006 | 489 | 2006 |
Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in … AJ Law, JE Kleinman, DR Weinberger, CS Weickert Human molecular genetics 16 (2), 129-141, 2007 | 344 | 2007 |
Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia TM Hyde, BK Lipska, T Ali, SV Mathew, AJ Law, OE Metitiri, RE Straub, ... Journal of Neuroscience 31 (30), 11088-11095, 2011 | 339 | 2011 |
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses AJ Law, JFW Deakin Neuroreport 12 (13), 2971-2974, 2001 | 285 | 2001 |
Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients VZ Chong, M Thompson, S Beltaifa, MJ Webster, AJ Law, CS Weickert Schizophrenia research 100 (1-3), 270-280, 2008 | 212 | 2008 |
Glutamate receptors and transporters in the hippocampus in schizophrenia PJ Harrison, AJ Law, SL Eastwood Annals of the New York Academy of Sciences 1003 (1), 94-101, 2003 | 203 | 2003 |
Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain AJ Law, CS Weickert, TM Hyde, JE Kleinman, PJ Harrison Neuroscience 127 (1), 125-136, 2004 | 197 | 2004 |
Molecular Cloning of a Brain-specific, Developmentally Regulated Neuregulin 1 (NRG1) Isoform and Identification of a Functional Promoter Variant Associated with Schizophrenia*♦ W Tan, Y Wang, B Gold, J Chen, M Dean, PJ Harrison, DR Weinberger, ... Journal of Biological Chemistry 282 (33), 24343-24351, 2007 | 179 | 2007 |
The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology SL Eastwood, AJ Law, IP Everall, PJ Harrison Molecular psychiatry 8 (2), 148-155, 2003 | 175 | 2003 |
Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of … AJ Law, CS Weickert, TM Hyde, JE Kleinman, PJ Harrison American Journal of Psychiatry 161 (10), 1848-1855, 2004 | 171 | 2004 |
Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls KK Nicodemus, AJ Law, E Radulescu, A Luna, B Kolachana, ... Archives of general psychiatry 67 (10), 991-1001, 2010 | 167 | 2010 |
Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain WT Kao, Y Wang, JE Kleinman, BK Lipska, TM Hyde, DR Weinberger, ... Proceedings of the National Academy of Sciences 107 (35), 15619-15624, 2010 | 166 | 2010 |
Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation AJ Law, CS Weickert, MJ Webster, MM Herman, JE Kleinman, ... European journal of neuroscience 18 (5), 1197-1205, 2003 | 166 | 2003 |
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy AJ Law, Y Wang, Y Sei, P O’Donnell, P Piantadosi, F Papaleo, RE Straub, ... Proceedings of the National Academy of Sciences 109 (30), 12165-12170, 2012 | 157 | 2012 |
Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains JE Kleinman, AJ Law, BK Lipska, TM Hyde, JK Ellis, PJ Harrison, ... Biological psychiatry 69 (2), 140-145, 2011 | 110 | 2011 |
Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice IH Deakin, AJ Law, PL Oliver, MH Schwab, KA Nave, PJ Harrison, ... Neuroreport 20 (17), 1523-1528, 2009 | 99 | 2009 |
Perinatal Phosphatidylcholine Supplementation and Early Childhood Behavior Problems: Evidence for CHRNA7 Moderation RG Ross, SK Hunter, MC Hoffman, L McCarthy, BM Chambers, AJ Law, ... American Journal of Psychiatry 173 (5), 509-516, 2016 | 95 | 2016 |
Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder AJ Law, Q Pei, M Walker, H Gordon-Andrews, CS Weickert, J Feldon, ... Neuropsychopharmacology 34 (6), 1381-1394, 2009 | 90 | 2009 |
Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation IH Deakin, W Nissen, AJ Law, T Lane, R Kanso, MH Schwab, KA Nave, ... Cerebral cortex 22 (7), 1520-1529, 2012 | 88 | 2012 |