Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 271 | 2020 |
Toward targeting inflammasomes: insights into their regulation and activation S Christgen, DE Place, TD Kanneganti Cell research 30 (4), 315-327, 2020 | 215 | 2020 |
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ... Cell reports 37 (3), 2021 | 180 | 2021 |
Programming inflammatory cell death for therapy S Christgen, RE Tweedell, TD Kanneganti Pharmacology & therapeutics 232, 108010, 2022 | 129 | 2022 |
Role of proline in pathogen and host interactions SL Christgen, DF Becker Antioxidants & redox signaling 30 (4), 683-709, 2019 | 116 | 2019 |
Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution W Leung, CD Shaffer, LK Reed, ST Smith, W Barshop, W Dirkes, ... G3: Genes, Genomes, Genetics 5 (5), 719-740, 2015 | 106 | 2015 |
Inflammasomes and the fine line between defense and disease S Christgen, TD Kanneganti Current opinion in immunology 62, 39-44, 2020 | 102 | 2020 |
Galactosaminogalactan activates the inflammasome to provide host protection B Briard, T Fontaine, P Samir, DE Place, L Muszkieta, RKS Malireddi, ... Nature 588 (7839), 688-692, 2020 | 86 | 2020 |
Structure and characterization of a class 3B proline utilization A: ligand-induced dimerization and importance of the C-terminal domain for catalysis DA Korasick, TT Gamage, S Christgen, KM Stiers, LJ Beamer, MT Henzl, ... Journal of Biological Chemistry 292 (23), 9652-9665, 2017 | 23 | 2017 |
Methods for determining the reduction potentials of flavin enzymes SL Christgen, SM Becker, DF Becker Methods in Enzymology 620, 1-25, 2019 | 22 | 2019 |
Evidence that the C-terminal domain of a type B PutA protein contributes to aldehyde dehydrogenase activity and substrate channeling M Luo, S Christgen, N Sanyal, BW Arentson, DF Becker, JJ Tanner Biochemistry 53 (35), 5661-5673, 2014 | 17 | 2014 |
Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis). Front Cell Infect Microbiol 10: 237 S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Int J Cancer 149, 1408-1420, 2020 | 14 | 2020 |
Hierarchical cell death program disrupts the intracellular niche required for Burkholderia thailandensis pathogenesis DE Place, S Christgen, S Tuladhar, P Vogel, RKS Malireddi, ... MBio 12 (3), 10.1128/mbio. 01059-21, 2021 | 9 | 2021 |
Sepsis take-out: inhibiting bacterial deliveries S Christgen, TD Kanneganti Immunity 54 (3), 399-401, 2021 | 7 | 2021 |
Discovery of the membrane binding domain in trifunctional proline utilization A SL Christgen, W Zhu, N Sanyal, B Bibi, JJ Tanner, DF Becker Biochemistry 56 (47), 6292-6303, 2017 | 6 | 2017 |
Identification of a conserved histidine as being critical for the catalytic mechanism and functional switching of the multifunctional proline utilization A protein MA Moxley, L Zhang, S Christgen, JJ Tanner, DF Becker Biochemistry 56 (24), 3078-3088, 2017 | 4 | 2017 |
Redox modulation of oligomeric state in proline utilization A DA Korasick, AC Campbell, SL Christgen, S Chakravarthy, TA White, ... Biophysical journal 114 (12), 2833-2843, 2018 | 3 | 2018 |
The IFN‐inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice S Christgen, DE Place, M Zheng, B Briard, M Yamamoto, TD Kanneganti European journal of immunology 52 (2), 285-296, 2022 | 2 | 2022 |
Probing the function of a ligand-modulated dynamic tunnel in bifunctional proline utilization A (PutA) DA Korasick, SL Christgen, IA Qureshi, DF Becker, JJ Tanner Archives of biochemistry and biophysics 712, 109025, 2021 | 2 | 2021 |
Inflammasomes as integral components of PANoptosomes in the regulation of cell death RE Tweedell, S Christgen, TD Kanneganti Inflammasome Biology, 525-538, 2023 | 1 | 2023 |