| Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1 M Liang, C Mallari, M Rosser, HP Ng, K May, S Monahan, JG Bauman, ... Journal of Biological Chemistry 275 (25), 19000-19008, 2000 | 254 | 2000 |
| Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor J Hesselgesser, HP Ng, M Liang, W Zheng, K May, JG Bauman, ... Journal of Biological Chemistry 273 (25), 15687-15692, 1998 | 240 | 1998 |
| A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection R Horuk, C Clayberger, AM Krensky, Z Wang, HJ Gröne, C Weber, ... Journal of Biological Chemistry 276 (6), 4199-4204, 2001 | 169 | 2001 |
| Structure-activity studies of antitumor agents based on pyrrolo [1, 2-a] benzimidazoles: new reductive alkylating DNA cleaving agents I Islam, EB Skibo, RT Dorr, DS Alberts Journal of medicinal chemistry 34 (10), 2954-2961, 1991 | 129 | 1991 |
| CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model R Horuk, S Shurey, HP Ng, K May, JG Bauman, I Islam, A Ghannam, ... Immunology Letters 76 (3), 193-201, 2001 | 119 | 2001 |
| Discovery of novel non-peptide CCR1 receptor antagonists HP Ng, K May, JG Bauman, A Ghannam, I Islam, M Liang, R Horuk, ... Journal of medicinal chemistry 42 (22), 4680-4694, 1999 | 103 | 1999 |
| Structure-activity studies of benzimidazole-based DNA-cleaving agents. Comparison of benzimidazole, pyrrolobenzimidazole, and tetrahydropyridobenzimidazole analogs EB Skibo, I Islam, MJ Heileman, WG Schulz Journal of medicinal chemistry 37 (1), 78-92, 1994 | 101 | 1994 |
| Design, synthesis and SAR of a series of 2-substituted 4-amino-quinazoline neuropeptide Y Y5 receptor antagonists H Rueeger, P Rigollier, Y Yamaguchi, T Schmidlin, W Schilling, ... Bioorganic & medicinal chemistry letters 10 (11), 1175-1179, 2000 | 91 | 2000 |
| Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor M Liang, M Rosser, HP Ng, K May, JG Bauman, I Islam, A Ghannam, ... European journal of pharmacology 389 (1), 41-49, 2000 | 83 | 2000 |
| Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites. P Du, JA Salon, JA Tamm, C Hou, W Cui, MW Walker, N Adham, ... Protein engineering 10 (2), 109-117, 1997 | 73 | 1997 |
| Pyrrolo [1, 2-a] benzimidazole-based quinones and iminoquinones. The role of the 3-substituent on cytotoxicity WG Schulz, I Islam, EB Skibo Journal of medicinal chemistry 38 (1), 109-118, 1995 | 68 | 1995 |
| Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity I Islam, J Bryant, YL Chou, MJ Kochanny, W Lee, GB Phillips, H Yu, ... Bioorganic & medicinal chemistry letters 17 (14), 3814-3818, 2007 | 64 | 2007 |
| A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa)–part II: enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis YX Wang, V da Cunha, J Vincelette, L Zhao, M Nagashima, K Kawai, ... Thrombosis and haemostasis 97 (01), 54-61, 2007 | 60 | 2007 |
| Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517 I Islam, G Brown, J Bryant, P Hrvatin, MJ Kochanny, GB Phillips, S Yuan, ... Bioorganic & medicinal chemistry letters 17 (14), 3819-3825, 2007 | 53 | 2007 |
| A novel P2Y12 adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models YX Wang, J Vincelette, V da Cunha, B Martin-McNulty, C Mallari, RM Fitch, ... Thrombosis and haemostasis 97 (05), 847-855, 2007 | 53 | 2007 |
| Synthesis and physical studies of azamitosene and iminoazamitosene reductive alkylating agents. Iminoquinone hydrolytic stability, syn/anti isomerization, and electrochemistry I Islam, EB Skibo The Journal of Organic Chemistry 55 (10), 3195-3205, 1990 | 51 | 1990 |
| Piperazine derivatives and their use as anti-inflammatory agents JG Bauman, BO Buckman, AF Ghannam, JE Hesselgesser, R Horuk, ... US Patent 6,207,665, 2001 | 47 | 2001 |
| Piperazine derivatives and their use as anti-inflammatory agents JG Bauman, BO Buckman, AF Ghannam, JE Hesselgesser, R Horuk, ... US Patent 6,207,665, 2001 | 47 | 2001 |
| Aryl sulfonamides and sulfamide derivatives and uses thereof I Islam, DS Dhanoa, JM Finn, P Du, C Gluchowski, YT Jeon US Patent 6,211,241, 2001 | 43 | 2001 |
| The organic chemistry of the pyrrolo [1, 2-a] benzimidazole antitumor agents. An example of rational drug design EB Skibo, I Islam, WG Schulz, R Zhou, L Bess, R Boruah Synlett 1996 (04), 297-309, 1996 | 43 | 1996 |
