Modular probes for enriching and detecting complex nucleic acid sequences JS Wang*, YH Yan*, DY Zhang Nature chemistry 9 (12), 1222, 2017 | 36 | 2017 |
Low-level parental somatic mosaic SNVs in exomes from a large cohort of trios with diverse suspected Mendelian conditions T Gambin, Q Liu, JA Karolak, CM Grochowski, NG Xie, LR Wu, YH Yan, ... Genetics in Medicine 22 (11), 1768-1776, 2020 | 25 | 2020 |
Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics P Song, LR Wu, YH Yan, JX Zhang, T Chu, LN Kwong, AA Patel, ... Nature biomedical engineering 6 (3), 232-245, 2022 | 24 | 2022 |
Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang Nature biomedical engineering 5 (7), 690-701, 2021 | 22 | 2021 |
Confirming putative variants at≤ 5% allele frequency using allele enrichment and Sanger sequencing YH Yan, SX Chen, LY Cheng, AY Rodriguez, R Tang, K Cabrera, ... Scientific reports 11 (1), 1-9, 2021 | 16 | 2021 |
Detecting and quantitating low fraction DNA variants with low-depth sequencing P Song, SX Chen, YH Yan, A Pinto, LY Cheng, P Dai, AA Patel, DY Zhang bioRxiv, 2020.04. 26.061747, 2020 | 3 | 2020 |
RNA Scaffold: Designed to Co-localize Enzymes. ZTGEM 2012), M Chen Methods in molecular biology (Clifton, NJ) 1316, 105-112, 2014 | 3* | 2014 |
Encoding multiple digital DNA signals in a single analog channel YH Yan, DY Zhang, LR Wu Nucleic Acids Research 48 (11), e65-e65, 2020 | 1 | 2020 |
925P Analytical performance of a next-generation sequencing (NGS) assay kit for assessing homologous recombination deficiency (HRD) from solid tumor samples L Liu, K Roessler, S Bilke, Y Ding, D Erlandson, Y Fu, B Hariharan, S Katz, ... Annals of Oncology 33, S969, 2022 | | 2022 |
High sensitivity qPCR microsatellite instability detection in FFPE tissue YH Yan, B Young, Z Wang, A Yaseen, A Pinto, D Zhang Cancer Research 82 (12_Supplement), 2806-2806, 2022 | | 2022 |
Molecular hybridization probes for complex sequence capture and analysis D Zhang, J Wang, Y Yan WO Patent US20200080136A1, 2020 | | 2020 |
Symbolic Sequencing of DNA and RNA via sequence encoding DY Zhang, Y Yan WO Patent WO2019046768A1/US62/552,652, 2019 | | 2019 |
Rationally Designed Hybridization Systems for Nucleic Acid Diagnostics and Sequence Analysis YH Yan Rice University, 2019 | | 2019 |