The IRF family transcription factors in immunity and oncogenesis T Tamura, H Yanai, D Savitsky, T Taniguchi Annu. Rev. Immunol. 26, 535-584, 2008 | 1374 | 2008 |
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses H Yanai, T Ban, ZC Wang, MK Choi, T Kawamura, H Negishi, M Nakasato, ... Nature 462 (7269), 99-103, 2009 | 795 | 2009 |
Regulation of immunity and oncogenesis by the IRF transcription factor family D Savitsky, T Tamura, H Yanai, T Taniguchi Cancer immunology, immunotherapy 59, 489-510, 2010 | 331 | 2010 |
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow M Shapiro-Shelef, KI Lin, D Savitsky, J Liao, K Calame The Journal of experimental medicine 202 (11), 1471-1476, 2005 | 278 | 2005 |
Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1 E Magnúsdóttir, S Kalachikov, K Mizukoshi, D Savitsky, ... Proceedings of the National Academy of Sciences 104 (38), 14988-14993, 2007 | 190 | 2007 |
A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA MK Choi, ZC Wang, T Ban, H Yanai, Y Lu, R Koshiba, Y Nakaima, ... Proceedings of the National Academy of Sciences 106 (42), 17870-17875, 2009 | 148 | 2009 |
B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion D Savitsky, K Calame The Journal of experimental medicine 203 (10), 2305-2314, 2006 | 142 | 2006 |
Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus DA Savitsky, H Yanai, T Tamura, T Taniguchi, K Honda Proceedings of the National Academy of Sciences 107 (22), 10154-10159, 2010 | 98 | 2010 |
Regulation of the cytosolic DNA-sensing system in innate immunity: a current view H Yanai, D Savitsky, T Tamura, T Taniguchi Current opinion in immunology 21 (1), 17-22, 2009 | 92 | 2009 |
Selective FcγR co-engagement on APCs modulates the activity of therapeutic antibodies targeting T cell antigens JD Waight, D Chand, S Dietrich, R Gombos, T Horn, AM Gonzalez, ... Cancer Cell 33 (6), 1033-1047. e5, 2018 | 80 | 2018 |
Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1 CA Lord, D Savitsky, R Sitcheran, K Calame, JR Wright, JPY Ting, ... The Journal of Immunology 182 (5), 2948-2958, 2009 | 38 | 2009 |
INCAGN02385 is an antagonist antibody targeting the co-inhibitory receptor LAG-3 for the treatment of human malignancies D Savitsky, R Ward, C Riordan, C Mundt, S Jennings, J Connolly, ... Cancer research 78 (13_Supplement), 3819-3819, 2018 | 22 | 2018 |
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody RB Gombos, A Gonzalez, M Manrique, D Chand, D Savitsky, B Morin, ... PLoS One 13 (4), e0191926, 2018 | 21 | 2018 |
Anti-OX40 antibodies M Van Dijk, EV Breous-Nystrom, G Ritter, D Schaer, ... US Patent 10,259,882, 2019 | 20 | 2019 |
Anti-PD-1 antibodies and methods of use thereof M Van Dijk, NS Wilson, CA Mundt, G Ritter, JD Wolchok, T Merghoub, ... US Patent 10,323,091, 2019 | 18 | 2019 |
Multiple roles for Blimp-1 in B and T lymphocytes D Savitsky, L Cimmino, T Kuo, GA Martins, K Calame Mechanisms of Lymphocyte Activation and Immune Regulation XI: B Cell Biology …, 2007 | 16 | 2007 |
Anti-CTLA-4 antibodies and methods of use thereof M Van Dijk, CA Mundt, G Ritter, D Schaer, JD Wolchok, T Merghoub, ... US Patent 10,144,779, 2018 | 12 | 2018 |
A novel agonist antibody (INCAGN01876) that targets the costimulatory receptor GITR AM Gonzalez, E Breous, ML Manrique, D Savitsky, J Waight, R Gombos, ... Cancer Research 76 (14_Supplement), 3220-3220, 2016 | 12 | 2016 |
Phase I/II, open-label, multiple ascending dose trial of AGEN2034, an anti–PD-1 monoclonal antibody, in advanced solid malignancies: results of dose escalation in advanced … C Drescher, KN Moore, JF Liu, DM O’Malley, EW Wang, JSZ Wang, ... Annals of Oncology 29, viii412-viii413, 2018 | 9 | 2018 |
Anti-OX40 antibodies M Van Dijk, EV Breous-Nystrom, V Seibert, G Ritter, D Schaer, ... US Patent 11,136,404, 2021 | 6 | 2021 |